Protein Alignment DCX-EMAP and eml3

DIOPT Version :10

• Sequence 1: NP_001261850.1
• Gene: DCX-EMAP / 39617
• FlyBaseID: FBgn0259099
• Length: 1118
• Species: Drosophila melanogaster
• Sequence 2: XP_005172258.2
• Gene: eml3 / 100533983
• ZFINID: ZDB-GENE-110304-3
• Length: 976
• Species: Danio rerio
• Alignment Length: 749
• Identity: 236/749 - (31%)
• Similarity: 362/749 - (48%)
• Gaps: 90/749 - (12%)

  Fly   372 ATGTALIAGSPIRRSRSRPSVVAAAPILPTDELPKVPLRGARPRS-----KSRPRILYAPESEIL 431
            |:.|.|:..||...||::..:.:|.        .:...||.:.:|     :.||..:|.|.
Zfish   279 ASSTNLLTRSPSLESRAKDLIASAG--------SQGSRRGTQNQSIKMFIRGRPITMYIPS---- 331

  Fly   432 RPNGEYTMLDIMKEEPTKVTIRGLRRTFYPPVHHAPADNSPPDKKLQLQWVHGYRGIDARRNLWV 496
                     :|...|..|:.:                    |.:||.|.||:||||.|.|.||::
Zfish   332 ---------NIQNYEELKMDL--------------------PSQKLDLDWVYGYRGRDCRANLYL 367

  Fly   497 LPSGELLYYVAAVAVLFDRDEDAQRHYTGHTEDIMCMDVHPSRELVASGQKAGRDRKS---QAHV 558
            |||||.:|::|.|.||:......||||..||:.:.|:.:||.:..|||||.||.|:..   |..|
Zfish   368 LPSGEAVYFIACVVVLYHISNQKQRHYRKHTDCVRCLAIHPDKVRVASGQTAGVDKDGKPLQPFV 432

  Fly   559 RIWSTESLQTLYVFGMGELDSGVTAVAFSQLNGGSYILAVDSGRESILSVWQWQWGHLLGKVATL 623
            .||.:::|.||...|:|..:.||.|:|||..:||:::..:|...|.:||||.|.......:|.:.
Zfish   433 HIWDSKTLVTLQQIGLGIFERGVGAIAFSNSDGGTFLCVIDDSNEHMLSVWDWNKNIKQAEVKST 497

  Fly   624 QEGLSGAAFHPLDDNLIITHGRGHLAFW------HRRKDGFFERTDIVKQPSRSHVTSVQFEPDG 682
            .|.:....|.|.|.|.||:.|:.|:.||      ..:|.|.|.:   .|:|  ..|....|...|
Zfish   498 NEAVLAVDFSPTDTNNIISCGKSHVYFWTMSAGTMTKKQGIFGK---YKKP--KFVLCFVFSLTG 557

  Fly   683 DVITADSDGFITIYSVDS-------DGA---YFVRTEFEAHNKGIGCLIMLGEGTLLSGGEKDRK 737
            ||:|.||:|.|..:...:       .||   :.:..:..||...:..:.:|..|.:||||.||||
Zfish   558 DVLTGDSEGNILTWGKSAADIKTLGKGAKETFQIMKQTRAHEGSVFTMCILQGGAILSGGGKDRK 622

  Fly   738 IAAWDSLQNYKKIADTKLPEAAGGVRTIYPQRPGRNDG-NIYVGTTRNNILEGSLQRRFTQVVFG 801
            |..|.:  :.....:.::||..|.||||     ...|| .:.||||||.||.|:....|..:|.|
Zfish   623 IIRWSA--DLAPERECEIPEKFGAVRTI-----ADLDGEELLVGTTRNAILRGTFSDGFVAIVQG 680

  Fly   802 HGRQLWGLAAHPDDELYATAGHDKHVALW--RKNKLIW--TIQTGYECVALAFHPFG-TLAAGST 861
            |..::||||.||...::.|.|:|:.:.:|  ..::|.|  |::....|.  .|.|.| .::.|.:
Zfish   681 HVDEMWGLATHPTQNIFVTCGNDRQLCVWNAEDHRLDWCTTLEDSGLCA--DFCPNGAVVSVGLS 743

  Fly   862 EGHLLVINCENGAVMLTLRVCGSPLNCVAYNQVGDMIAMGSQNGSIYLFRVSRDGFSYKKVNKIR 926
            ....:|::.:...|:..|......|:.:.|:..|..:|:||.:..||::.|:..|..|.:..|..
Zfish   744 TARWVVLDLQTKEVVADLIDGNEQLSVMRYSPDGSFLAVGSHDNFIYIYSVTEGGRRYTRFGKCT 808

  Fly   927 G-SQPLTHLDWSMDGNFVQTVTIDFDLLFWD-AKSLSPERSPIAMKDVKWLTNNCTVGFLVAGQW 989
            | |..:||||||.||.|:.:.:.|:::|:|| |......|:....||.:|.:..|.:||.|.|.|
Zfish   809 GHSSFITHLDWSKDGKFIMSNSGDYEILYWDVASGCKLLRNRFESKDREWASYTCVLGFHVMGVW 873

  Fly   990 SNRYYSTTNTIVATCSRSAAHDMLASGDAEGYLRLFRYPCISPRAEFHESKVYSGMLACVRFLCG 1054
            ...  |....|.|.| ||.:..|:|..|....:.||:|||..|:|..::.:.:...:..|||...
Zfish   874 LEG--SDGTDINALC-RSHSERMVAVADDFCKVHLFQYPCPKPKAPSYKYEGHGSHVTNVRFTHN 935

  Fly  1055 DHTLITVGGTDASLMVWDIVEEXLKWPPWHRTAA 1088
            |..|:::||.|..::.|.:.......|..|..||
Zfish   936 DSHLLSLGGKDTCILQWRMKGAGTAEPKEHSAAA 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCX-EMAP	NP_001261850.1	DCX	166..253	CDD:214711
		DCX2_RP_like	300..372	CDD:340590	236/749 (32%)
		HELP	449..515	CDD:460922	25/65 (38%)
		WD40	520..562	CDD:459801	20/44 (45%)
		WD40 repeat	530..573	CDD:293791	18/45 (40%)
		WD40	548..959	CDD:441893	141/437 (32%)
		WD40 repeat	582..624	CDD:293791	14/41 (34%)
		WD40 repeat	627..664	CDD:293791	13/42 (31%)
		WD40 repeat	673..712	CDD:293791	12/48 (25%)
		WD40 repeat	718..801	CDD:293791	32/83 (39%)
		WD40 repeat	806..838	CDD:293791	12/35 (34%)
		WD40 repeat	846..880	CDD:293791	6/34 (18%)
		WD40	847..>1073	CDD:475233	70/228 (31%)
		WD40 repeat	886..918	CDD:293791	10/31 (32%)
		WD40 repeat	931..969	CDD:293791	15/38 (39%)
		WD40 repeat	1002..1037	CDD:293791	14/34 (41%)
eml3	XP_005172258.2	None