DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17839 and igdb-1

DIOPT Version :9

Sequence 1:NP_996085.2 Gene:CG17839 / 39616 FlyBaseID:FBgn0036454 Length:1656 Species:Drosophila melanogaster
Sequence 2:NP_502387.2 Gene:igdb-1 / 3565301 WormBaseID:WBGene00011418 Length:1029 Species:Caenorhabditis elegans


Alignment Length:1453 Identity:301/1453 - (20%)
Similarity:481/1453 - (33%) Gaps:519/1453 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   199 CNVHNILDGTTGIDPEA---------CERDFPGIVRCMADGRNHVPCCVDKQIPDLCQDMCRGEY 254
            |||..        ||.:         |..::|.:..|:||||||..||:.|.:...|.::|.|. 
 Worm     2 CNVAE--------DPSSFSTITIATTCRAEWPKVSPCIADGRNHTDCCLKKGVQHDCLEICSGS- 57

  Fly   255 TPFTDKLKTR-VSCVQHTLSGL-QCILKGVQLIPSSPTFVTIENVSETSVTIGWTAPDKLADRVS 317
               |.:|... |.|:...|..: |||.:|.:..||:|..|||..::..|||:.||.|:..|..|.
 Worm    58 ---TKELGVHSVLCLNLDLQAIYQCIRQGYETHPSAPGNVTISELTAHSVTVQWTEPNSNAHLVE 119

  Fly   318 GYTINLTTLHSFDEDELSGEIVHRTASD--SPESISLYSVPTNQTQLTLSNLSPLTMYAVIVTAT 380
            .||:       |......||.| ||..:  ||. :.|             .|.|.:.|.:.:.:.
 Worm   120 NYTL-------FIRKNEHGEAV-RTVKNVISPH-VEL-------------GLDPDSEYVLTLQSH 162

  Fly   381 NEFGSSLPTERLRFFTHTSASAAESKAGTTDKQAMPQLPDTRQCCEDNGMTHRMCLDKMCDPQKT 445
            :..|:|||:....|.|                     ||.||.                      
 Worm   163 SANGTSLPSTAKLFST---------------------LPTTRP---------------------- 184

  Fly   446 DQANLPDFMVCAPWSNITFNCLANNIDHTPCCRARGIPSACFPLCAGKLTSLDFSLFKCLRFMSE 510
                                                      |||                    
 Worm   185 ------------------------------------------PLC-------------------- 187

  Fly   511 YNSCLFQGYGVLADPPSKLRTVAKTDSFVILDWNKPKRLADTVSTYHVKFRRLGVGDDYLTVEKR 575
                      .:.:|      :...|..|:        :.|.|:.....||..|.|         
 Worm   188 ----------TIGEP------IYMNDGRVM--------ICDAVNPCPNGFRCTGAG--------- 219

  Fly   576 QPPLILEGLESDIYYEFYVVSINAYGKSEASPRLITRTLPAEPVQQTAARYNMTTCCQASGLLPQ 640
                      ||:.|                         ..|...|.:....|:||:...:...
 Worm   220 ----------SDLSY-------------------------CCPHDGTHSSEEFTSCCKEQKMPES 249

  Fly   641 CAPLCSYNIRLSDIERLGPACRAQMPILARCAAGGRDHSPCCSRRGVINACMPLCRGVMPLALTT 705
            |...|.||:.|.:      :|:..:....:||:.|.||..||.:..|...|...|  :.|..:  
 Worm   250 CMSSCQYNMTLPE------SCKENLNTWVQCASEGHDHLRCCLQEEVSKPCQTAC--MHPFTV-- 304

  Fly   706 KSSSASAAAAATSSSSGATAATSASATSNSNAAGAPSSSSSSASSGTSSNVPDCLSYAGNILQCF 770
                                               |:.              :|.|.......||
 Worm   305 -----------------------------------PAD--------------ECFSEVSKYRTCF 320

  Fly   771 EEGTQNIPGPPEDVHATFVNQSSVSLAWTQPDVDNSNSSSSGNASPGDMITGDELAAGAVDPANA 835
            ....|.:|....:|..:.:::.|.:::|                                     
 Worm   321 SAAHQALPAAVRNVEVSSISKDSATISW------------------------------------- 348

  Fly   836 GKDVPNAGDATSGTTGTEDIE-----FIVQYGKVNNMTMYETVAKLENELTTNETSIDL---TNL 892
                             ||:|     |.||        ::|   |..|.:.|..:|.|:   .:|
 Worm   349 -----------------EDLEANIIVFRVQ--------LFE---KGGNLIKTENSSADIFRFIDL 385

  Fly   893 DANALYRITVVTRGKFGTSLPASMLLLNTTDQQRTGEAWGAPSP--PHSLTVVAHSATWMQLTWQ 955
            :.|..|.:.|......|...|:    .|.|...:..:.:....|  |..|.:..:|...:.:||.
 Worm   386 EPNKDYSVRVTAINFLGEGPPS----WNATFTTKPAQIYEGDRPVAPEKLRISWNSGPRVNVTWD 446

  Fly   956 PPEYAHPHERIT----YRVYHKAMRAEQ---FIKIETKLAWLRMNNLKPSSQHVLYVEAVGERGD 1013
            |.......|.:|    |.:|:  :..||   :..:.|...|:.|.:|:..:.:.:||.|..:...
 Worm   447 PVSVRRNAEVVTKPIEYTIYY--LDTEQSSTWTTLRTNQTWVVMRDLRKDALYYVYVTAKEDNRT 509

  Fly  1014 SLPSE--TLVAWTD-PALPAFVDPPTV-----HPADNIPEGGSMTILCLAFGNPAP------TIS 1064
            |..|.  |::|..| |.||    .||:     |.......|..::|.|     ..|      .|.
 Worm   510 SRSSSIITILAQKDSPGLP----EPTIVIEPDHKDGVFSPGEKISINC-----SLPNIKKHLNID 565

  Fly  1065 LYVGGHLVRQDASRHMVTVIHNVSAD--MEHVSCYADNGYGVPMQATRRVNICYPPKIQAAGITV 1127
            |.||.|:|:.|  ...:.||....||  |:..:|...:..|....|.:.:.:.....:......:
 Worm   566 LTVGSHVVQND--HGALWVILETEADEAMDTATCAVSDTDGRQHVAMKHLVLERKASVTMKKDKI 628

  Fly  1128 ANIGDE-IELRCT-----VDSKPAPKTIFWREKDGRVPVINGGNYFISVKANESRPSIYTMSLRI 1186
            ..:.|: :|:.|.     :|    ||..|  ||||:    .....|:::|..|:.   |.....|
 Worm   629 RVLDDQSVEIECIYRGGGLD----PKISF--EKDGK----KASRGFLNLKKTEAG---YVAKWHI 680

  Fly  1187 SKLQANDVGDYFCHADNPFGATTTPVSVRIRNTPALNHN---VSECCAAQNVSMACRSACSYYVD 1248
            .|::..|.|.|.|...:..|:.....|..|.:|..|..|   :.:||..:.::..|..||:....
 Worm   681 RKVKQEDAGFYKCVVTSSDGSRVEASSEVIFSTETLPVNPKLILQCCEDEGITGDCLQACNIGRT 745

  Fly  1249 FDAIADRPECIVDFDKLMRCAADGSDHRSCCADEHVPRKCLNWCRGESVRSKEICSLQYARTIVG 1313
            ..:|.:: .|......|::||:|..||..||....|..|||..|.|:|......|| ::|.:|:.
 Worm   746 SLSIKNQ-NCTRFAVSLLKCASDIRDHSDCCIASGVTSKCLPLCSGDSFSPDIDCS-EHAVSIMT 808

  Fly  1314 CFEKNRDRLPGPPENIVVSVVSDSEVNVRWDAP-TKNPNAVDGYRIFYHEAAILPPTSSSSSGSP 1377
            |..|:.:..|....|:.:. .|:.:||:.||.| ||:   ...:.::|.:|              
 Worm   809 CSVKSHEHAPSEVSNVRIK-ASEGKVNIEWDYPLTKD---YKYFAVYYRKA-------------- 855

  Fly  1378 SSDSGSSMENPGMDTLAAMNNATSMGNSNNAMAALEIRRIDVKDTTISINGLKKDV----LYELV 1438
             .|......                                 |..||..| ::.||    .||:.
 Worm   856 -HDDHEDWH---------------------------------KLKTIQQN-IELDVDPSEDYEVG 885

  Fly  1439 VKAGNSYGASVL--------TDPIRFTLGEHHVTSATSSYSSAVGTISGIVASILAILLAAAAIV 1495
            :.|.|:.|.|.|        ::|.|         ||:...|||...:  ::..:..:|:|..|::
 Worm   886 ILAANALGHSRLMYSAIPKDSEPRR---------SASKGSSSAFWIV--VILVVFGVLIAGLAVL 939

  Fly  1496 FYRRQ-----RSSYGKSANGN---VAFENPTYTR--GLEQVQL------PTVTSAITTQNGNHHG 1544
            ..||:     ....|:..:.|   ||||||.|..  |..:|::      .|..:|..||:    .
 Worm   940 SKRRELPYPIGKFIGRRNDPNQPTVAFENPAYGEPWGGAEVEIRGLGGSATTGTAAATQS----E 1000

  Fly  1545 MSSSN---NNGSSNSHSHGRNGI 1564
            ..|:|   |:.:.|||.: |||:
 Worm  1001 WQSANLEANSTTDNSHEY-RNGM 1022

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17839NP_996085.2 ig 33..116 CDD:278476
IG_like 35..129 CDD:214653
DB 185..278 CDD:279948 26/89 (29%)
FN3 286..396 CDD:238020 33/111 (30%)
DB 424..515 CDD:279948 3/90 (3%)
FN3 524..613 CDD:238020 12/88 (14%)
DB 631..>704 CDD:279948 19/72 (26%)
FN3 778..915 CDD:238020 22/144 (15%)
FN3 934..1024 CDD:238020 24/100 (24%)
Ig 1034..1104 CDD:299845 20/82 (24%)
IG_like 1126..1216 CDD:214653 23/95 (24%)
Ig 1134..1216 CDD:299845 22/86 (26%)
DB 1229..1315 CDD:279948 26/85 (31%)
FN3 1323..1457 CDD:238020 28/146 (19%)
igdb-1NP_502387.2 DB 1..80 CDD:279948 26/89 (29%)
FN3 88..178 CDD:238020 33/111 (30%)
Lustrin_cystein 187..227 CDD:291299 13/127 (10%)
DB 240..321 CDD:279948 23/139 (17%)
FN3 328..414 CDD:238020 24/154 (16%)
FN3 425..518 CDD:238020 22/94 (23%)
ig 628..701 CDD:278476 21/85 (25%)
DB 726..809 CDD:279948 26/84 (31%)
FN3 818..895 CDD:214495 24/129 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 52 1.000 Domainoid score I7668
eggNOG 1 0.900 - - E1_28IYF
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H82136
Inparanoid 1 1.050 260 1.000 Inparanoid score I1914
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm14390
orthoMCL 1 0.900 - - OOG6_115563
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X11806
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
109.720

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