Protein Alignment Helz and CT55

DIOPT Version :10

• Sequence 1: NP_648725.2
• Gene: Helz / 39613
• FlyBaseID: FBgn0036451
• Length: 2103
• Species: Drosophila melanogaster
• Sequence 2: NP_001026875.1
• Gene: CT55 / 54967
• HGNCID: 26047
• Length: 264
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 48/256 - (18%)
• Similarity: 76/256 - (29%)
• Gaps: 88/256 - (34%)

  Fly  1009 ERLY---DHYPSNFPCKI-----LLCENYRAHEAIIRFTSELFYEQKLVASGKQPRHDRFYPLTF 1065
            |.:|   |....|.|.|:     ::.|..:.|           |..:.:.....|||       .
Human    55 ESIYFSSDVVTGNVPLKVGQKVNVVVEEDKPH-----------YGLRAIKVDVVPRH-------L 101

  Fly  1066 FTTRGED---------VQDKNSTAFYNNAEVYEVVERVSELRKRWPSAWGKLNDTSIGIMTPYSD 1121
            :.....|         |...|....|.:..:|..:..|||                  ...||..
Human   102 YGAGPSDSGTRVLIGCVTSINEDNIYISNSIYFSIAIVSE------------------DFVPYKG 148

  Fly  1122 QVFRIRSELRKRRMGGISVERVLNVQGKQFRAVFLSTVRTRRTCMPQGSAPGSASTTSIGDADA- 1185
            .:..:......    |||     |::....:.:  ..:.|...|:           ||:...:.
Human   149 DLLEVEYSTEP----GIS-----NIKATSVKPI--RCIHTEEVCI-----------TSVHGRNGV 191

  Fly  1186 -DYGF---LSNSKLLNTAITRAQSLVAVV-GDPVALCSIGRCRKVWERFIEICDEHKSLFG 1241
             ||..   |.:.||.:..:.:...:|.|| .:.:..|.|      | |.|.|...|||..|
Human   192 IDYTIFFTLDSVKLPDGYVPQVDDIVNVVMVESIQFCFI------W-RAISITPVHKSSSG 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Helz	NP_648725.2	zf-CCCH	329..353	CDD:459885
		DEXXQc_HELZ	805..1030	CDD:350835	7/28 (25%)
		DNA2	<925..1236	CDD:440729	44/249 (18%)
CT55	NP_001026875.1	S1-like	41..>78	CDD:464176	6/22 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..264		2/4 (50%)