Protein Alignment Helz and armi

DIOPT Version :10

• Sequence 1: NP_648725.2
• Gene: Helz / 39613
• FlyBaseID: FBgn0036451
• Length: 2103
• Species: Drosophila melanogaster
• Sequence 2: NP_647816.2
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Alignment Length: 1262
• Identity: 297/1262 - (23%)
• Similarity: 479/1262 - (37%)
• Gaps: 332/1262 - (26%)

  Fly   184 LDKYSKLLSNKGLKKREQQQQQQQQQQQQNGNGIGSYASSSSSSSTGSSSTMSSSSTSLHKTNDL 248
            ||:.:..|..|      ..:::..||.:.|.|.|....|:..:..|...|.|..|..|
  Fly    23 LDRENSFLDQK------LMEEKMDQQLKANPNEINGVLSNKIAELTHGLSEMDVSKES------- 74

  Fly   249 LAAMKLTAGKHQPGSGDGSGSDQG--DQAAPSTT-------------CSYCTITFQTRNELR--- 295
                ..||.|....|.||   |:|  |:.....|             |....:||.|...:|
  Fly    75 ----SCTARKGVITSLDG---DRGVIDKDVLFETKVAEDIILDLHVGCVVEYLTFTTGEAMRVVK 132

  Fly   296 -----QHCQTEAHQKVIMSDEGRDWKWRPPPRGYTLDTYSLCETFSEAHI------CHYGAQCVE 349
                 :|...:..||.|  ::..|......|..:..:|.|:....|:...      ..||...||
  Fly   133 VKSILEHSWEDTSQKEI--EKAVDNLKNEKPTFFNTETRSVLGLISQRLASSIDVETEYGQLTVE 195

  Fly   350 AHG----------------------------QDELNEWKERFEYRRMRMQKACEKELYGKSYTEQ 386
            ...                            |.|:.|..:.|.   .|:|:. ||.:..:.|...
  Fly   196 LDNIEMNFIPTNGDRVRLECNIQLDDGFVDKQGEILEVTKLFP---TRIQEG-EKCIVERVYVHM 256

  Fly   387 VL---DRWIQAT--------------APERVMCE---------RVPDME-----ARCEQQ----- 415
            |:   :.:|..|              ..:.:.|:         ::..:|     .:..||
  Fly   257 VVLGPETYILKTDLPTGTDLHLGDIVLADLIECQYSKFTRRAIKITPLEKNFGATKLTQQSSMGS 321

  Fly   416 -------LVTSISSKTSKREWLFQLETKKPLKAVALLQDAHRNHFALKSIKMCKPTESSMELKSD 473
                   .||.::...:...|      :|...::.|..:.:|. ..|:||.:|..:||.:.:.|.
  Fly   322 SGSGKAVTVTGVNRFITAELW------QKESVSLKLTNNLNRT-LRLESITVCNDSESQLSVVSP 379

  Fly   474 QEWLAGSSSQSETSNEDSATLIHEITVEFHTEIYGTF--RQAICFDVGQEPLLVRHLCVDVLPVN 536
            .|       ..|.|:....|    :|.|.||:..|..  :..:.||:    |.||.: ..|:...
  Fly   380 LE-------SKEISSGSEIT----VTFEIHTQFLGEAIEKYVLNFDL----LKVRRV-FTVIVCK 428

  Fly   537 DAEKIEEIKRDIINSSATRWDVANTQ-LTRF----------ETTIGTHLKTE-----AYLSDLEH 585
            ..|::.|.::.:|.:.|......|:| .:||          :...|..:.|:     ..|...|.
  Fly   429 TKEEVAEAEKRMIAAEALMAPGRNSQERSRFYANQVWCNKVDVIPGQQIVTKRRFVALRLGCFEV 493

  Fly   586 ERELLERYPCPRAATFTLTQSTI--VEKR-------LTQNNYRSRIHELLSVEEIARYEQIARYN 641
            .:||  |..|   .|....|..|  :|:.       |:...|..|...||.:|||..:.....|:
  Fly   494 PKEL--RQIC---LTSERRQEMIKAIEQHYSFLTEPLSIKTYMHRFRLLLHLEEIECFVNFRNYD 553

  Fly   642 VRTRLTVASNYILTPAGMATSTAKYSLAGELFALMRLGKDISEDTSPGR--LILSNCSSVYISKP 704
             |.|                  |.:...||...|.      .|:.:..|  |::.:...| |:..
  Fly   554 -RDR------------------AHFLRDGEFLTLQ------IENLAERRPSLVIGDTLRV-INPW 592

  Fly   705 EDPDSKADPTKRAVYEALIEDKGKNVIYLKLSAKCVEAMALQADTELEVDIQFQLNRMPYCEWHN 769
            .||||:.  ||.  ||.:|.    .|::.::..|...:...:.:.| :..::|..:|..:.:.|:
  Fly   593 SDPDSQT--TKS--YEGIIH----KVLFDRILLKFHSSFQEKYNGE-DYRLEFYFSRYSFRKQHH 648

  Fly   770 AVDKIT-----DFRLIFPATELEPSIP-------------WTPKKQWADSCEPKLNAKQREAVNA 816
            |:.||.     ||  :||:...:...|             :..|.:|.:.   .||:.|:.||..
  Fly   649 AISKIVGVMGEDF--LFPSKVTKRENPQLDVYMKDDDMYLYDSKLEWYNQ---SLNSIQKRAVFN 708

  Fly   817 ITTALSIKLPPILLIGPFGTGKTYTLAQAIKQLLTQ-PEAKILICTHSNSAADLYIKEYLHPWIE 880
            |....:..: |.:|.||.|:|||.||.:.:.||:.. |.|:||:.|.|||:|||..|..:.   .
  Fly   709 ILRGEAENI-PYVLFGPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRLID---S 769

  Fly   881 EGLKEATPLR-VYYHKRWSATVNGVVQKYCITDGVGNF---------------LRPTVEDIMRHR 929
            :.|.:...:| |.|::.....:...:..||.|..||..               ||...:.|..||
  Fly   770 KALLQGDFIRLVSYNQVEKDLIPPEIMSYCATSDVGAVGSCEDKMMVTESGLKLRCQAKFIGTHR 834

  Fly   930 IVVVTLSISMELATLGLPKGLFTHIFLDEAAQAMECEAIMPLA-LANDSTRIVLAGDHMQMSPEL 993
            |.:.|.:.......||.|.|.|||:..|||.|..|.|.::|:. |....:::||:||..|:...:
  Fly   835 ITISTCTTLGNFLQLGFPAGHFTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQSIV 899

  Fly   994 FSAFAKERKLHISLLERLYDHYP-----SNFP----------CKILLCENYRAHEAIIRFTSELF 1043
            .|..|.:....||.||||.:..|     ..||          .|:|.  ||||..:|:...|.||
  Fly   900 TSRIASKMGFSISFLERLLERSPYRKDLQRFPESSGYNPLVLTKLLY--NYRALPSIMSIYSRLF 962

  Fly  1044 YEQKL--VASGKQPRHDRF-----------------YPLTFFTTRGEDVQDKNSTAFYNNAEVYE 1089
            |:.:|  |.|.|..|..|.                 :...|:...||:.|:.:|.:::|..||.|
  Fly   963 YDDELIPVLSEKDSRESRLLSKLRCVFESEKDIPQAHGTFFYGIIGENRQNNDSPSWFNPQEVRE 1027

  Fly  1090 VVERVSELRKRWPSAWGKLNDTSIGIMTPYSDQVFRIRS-----ELRKRRMGGISVERVLNVQGK 1149
            |......|.:      ..:....|||:|||..||..:||     ::...::|  |||   ..||:
  Fly  1028 VFLMTIALYR------ANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIG--SVE---EFQGQ 1081

  Fly  1150 QFRAVFLSTVRTRRTCMPQGSAPGSASTTSIGDADADYGFLSNSKLLNTAITRAQSLVAVVGDPV 1214
            :...:.:||||:....:..             ||....||:..||.||.|::||::::.:.|:|
  Fly  1082 ERDIILISTVRSSEEILRM-------------DARFSLGFVRCSKRLNVAVSRARAMMIIFGNP- 1132

  Fly  1215 ALCSIGRCRKVWERFIEICDEHKSLFG 1241
            .|.::..|   |.:.|..|.::.:.||
  Fly  1133 HLLAVDEC---WRQLILFCVKNNAYFG 1156

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Helz	NP_648725.2	zf-CCCH	329..353	CDD:459885	6/57 (11%)
		DEXXQc_HELZ	805..1030	CDD:350835	80/257 (31%)
		DNA2	<925..1236	CDD:440729	102/350 (29%)
armi	NP_647816.2	DEXXQc_Mov10L1	697..949	CDD:350836	80/257 (31%)
		DNA2	<829..1148	CDD:440729	101/348 (29%)