Protein Alignment Tdrd3 and tdrd-3

DIOPT Version :10

• Sequence 1: NP_648724.1
• Gene: Tdrd3 / 39612
• FlyBaseID: FBgn0036450
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_503358.1
• Gene: tdrd-3 / 178599
• WormBaseID: WBGene00021748
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 829
• Identity: 186/829 - (22%)
• Similarity: 294/829 - (35%)
• Gaps: 279/829 - (33%)

  Fly     6 KLREVGWYLTEEGLKIVTTAV---------GSEDVRKIVNDALNRDLRDIGGGAL--PAKREDAT 59
            :||:.|||:.|.    .|:.:         ||| :.|::   ||.|||:.|..::  ..|:||..
 Worm     3 QLRKDGWYINES----QTSQLFDDELLPKNGSE-IEKVI---LNEDLRNFGEASIINLLKKEDFV 59

  Fly    60 LPGKIVLQVQRVRNIAAPKANEE---SKAAPRLLQLDLSDGQNSIKALELEPVPQLNLNVAPGSK 121
            ..|..|||:.|.||::.|:..||   :..|..:::|..:||.:||.||.|:.:|.:..:..||:|
 Worm    60 FEGPCVLQLLRYRNVSVPRIKEELNQTDPAHSIIRLFFTDGHSSISALLLQSIPGITSDTPPGTK 124

  Fly   122 IYFKAEKLQLMQGFLLLKSSEIQLLGGRVDALYEKWDLARTMMRYARSGRPLNGTSAPPPWVAFG 186
            |.... |:.:..|||:|...:|::|||:||.:.|||::.::.:|.......:...:..|.|::||
 Worm   125 ILILG-KVDVEGGFLILGKKDIRILGGKVDEMIEKWNVEKSSVRAGGFKSSVGKGTGAPKWISFG 188

  Fly   187 RKIDSNAESEMNFKSLGEGDKDKPAKENE----EFNAMRTEAIAVATKAGGKKIFGGGGQNIIDH 247
            :: ....:.|..||:  .....|..||.|    :|:..|.|
 Worm   189 KR-GQKGQLEKGFKA--NSVMPKTQKEGEDADDDFSKNRAE------------------------ 226

  Fly   248 NVKKILDKGFSEEEARSALSATRNNLERALYNLKRRSEAGGVGPIESVGRPGR----GDRPPREG 308
             :.|.||...::..|:..|:..                     |:::...|..    ..||.|:|
 Worm   227 -ILKDLDSDTAKTFAKPNLAPP---------------------PVKAPAPPKERRVPAARPARKG 269

  Fly   309 KRGASAKD-------EVEAPKPAANTTLFDFLTNKLPAKETPAASNAETFAAAPTAAPTAPP-TT 365
            :...:::|       |....||:...|||||:.....|            .|:..|....|| ..
 Worm   270 RGRKNSEDGPDVDVGEYANHKPSGPATLFDFIGGGAGA------------GASEKAVELLPPQNV 322

  Fly   366 NHFNPFKQYGSSRFSDSES--KPSAMGGGGKFADRSRFENNVSSSFAAHRGGHVGSSRGGGRNRG 428
            .|..  ::.|.....:||:  .|.|                                       |
 Worm   323 QHLT--EKMGKLNVKNSENFKYPGA---------------------------------------G 346

  Fly   429 GGRDERPPREERAYREDRPPREEKPPKEERP--------------PRERGA--FNDRAAGRYKPE 477
            |.||:||    .|.|:|....:...|:.:||              |:.|.|  |.||.. :.:|.
 Worm   347 GRRDQRP----AAARDDNRGPKNSAPQNQRPAAARDGNRGPKNPGPQNRAADYFRDRDR-QQRPS 406

  Fly   478 TPTVKTANRNGSDNVSLKPNSEIKPDHETTNGKDHTGNRRGSERGSNRGGSNRAENGNANGNRRN 542
            |.:|....|..|.|....|.|        .|...:.|:.||:::...:|..::...||....::.
 Worm   407 TGSVGQQPREVSRNFQNSPRS--------FNQNSNQGHPRGNQKSFQQGAPHQTPRGNQGNFQQQ 463

  Fly   543 KPAASLTSASSAAKSTNSAGDDFNARLSKITEETANLKVSSAPKRENRRKQGGQANRLAGSGTET 607
            .|...                            |.|......|.|      |||.:   |...:.
 Worm   464 GPPRG----------------------------TGNYFFQQGPPR------GGQFH---GGSQQG 491

  Fly   608 TQQQQPAQLHSQK-PEKAQTNQKHHNPRHNSQANYSQLANGYTYD--PSKIMGFQSKEANEFAMN 669
            .....|:|.|.:. .::||.|..   ||.|:|        |.:|.  |..:..|..:|
 Worm   492 PPPPPPSQHHPRGFQQQAQQNPP---PRGNNQ--------GQSYHGAPRGMGNFGHQE------- 538

  Fly   670 LLKSQGVTLPNEKQQEEEQQESPPMSFGPVSAPVSRAQPAPVAVPQAAPRDQFGMVPGDAWMWQK 734
                     |...||..:||...|                                     .|:.
 Worm   539 ---------PRNVQQSHQQQTGGP-------------------------------------QWRV 557

  Fly   735 GDLCMAKYWDDGRYYEAEITG-VSEKTCVVFFMGYGNHEEVLKVDILPI 782
            |..|:|. |.||..|.|.:|. :..:|.:|.:..||| ...:.||.|.|
 Worm   558 GAQCLAT-WTDGNLYPATVTELLPNRTAIVRYNEYGN-MHTIPVDFLII 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdrd3	NP_648724.1	RMI1_N	39..161	CDD:462527	47/126 (37%)
		UBA2_spUBP14_like	246..284	CDD:270483	5/37 (14%)
		Tudor_TDRD3	732..782	CDD:410484	18/50 (36%)
tdrd-3	NP_503358.1	RMI1_N	37..159	CDD:462527	45/122 (37%)
		Gag_spuma	<347..471	CDD:460872	34/164 (21%)
		Tudor_SF	555..>593	CDD:470623	13/38 (34%)