Protein Alignment bmm and PNPLA4

DIOPT Version :10

• Sequence 1: NP_001163445.1
• Gene: bmm / 39611
• FlyBaseID: FBgn0036449
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_004641.1
• Gene: PNPLA4 / 8228
• HGNCID: 24887
• Length: 253
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 90/247 - (36%)
• Similarity: 140/247 - (56%)
• Gaps: 4/247 - (1%)

  Fly     1 MNLSFAGCGFLGIYHVGVAVCFKKYAPHLL--LEKIGGASAGSLAACCLLCDLPLGSMTSDF-FR 62
            :|||||.||||||||:|.|....::...|:  ::...|||||||.|..||.........:.| ::
Human     4 INLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIEECNQFTYK 68

  Fly    63 VVNEARRYSLGPFSPSFNIQTCLLEGLQKHLPDDAHKRVNGRLHISLTRVYDGKNVIISEFESRE 127
            ...|.||.|.|..:|.::....|..|::..||..||:....|||:|:|.....:|.::|.|.|||
Human    69 FAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKTRENHLVSTFSSRE 133

  Fly   128 EVLQALLCACFIPGFSGILPPRFRGVRYMDGAFSDNLPILD-ENTITVSPFCGESDICPRDQSSQ 191
            ::::.||.:.|:|.::|:....::|.:::||..::.||||. ..|:|:|||.|..||.|:|:...
Human   134 DLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVTISPFSGRLDISPQDKGQL 198

  Fly   192 LFHLNWANTSIEISRQNINRFVRILFPPRPEFLSKFCQQGFDDALQFLHRNN 243
            ..::|.|...|.:|..|:.|..:.||||....:....|.||||.::||.:.|
Human   199 DLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTVKFLLKEN 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bmm	NP_001163445.1	Pat_iPLA2	1..245	CDD:132857	90/247 (36%)
PNPLA4	NP_004641.1	Pat_PNPLA4	5..250	CDD:132861	89/244 (36%)
		GXSXG. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161	41..45		3/3 (100%)
		DGA/G. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161	163..165		1/1 (100%)