DRSC/TRiP Functional Genomics Resources

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Protein Alignment bmm and Pnpla2

DIOPT Version :10

Sequence 1:NP_001163445.1 Gene:bmm / 39611 FlyBaseID:FBgn0036449 Length:553 Species:Drosophila melanogaster
Sequence 2:NP_001157161.1 Gene:Pnpla2 / 66853 MGIID:1914103 Length:486 Species:Mus musculus


Alignment Length:374 Identity:152/374 - (40%)
Similarity:222/374 - (59%) Gaps:33/374 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 NLSFAGCGFLGIYHVGVAVCFKKYAPHLLLE--KIGGASAGSLAACCLLCDLPLGSMTSDFFRVV 64
            |:|||||||||:||:|||.|.:::||.|:..  .|.|||||:|.|..|:....||...::...|.
Mouse     9 NISFAGCGFLGVYHIGVASCLREHAPFLVANATHIYGASAGALTATALVTGACLGEAGANIIEVS 73

  Fly    65 NEARRYSLGPFSPSFN----IQTCLLEGLQKHLPDDAHKRVNGRLHISLTRVYDGKNVIISEFES 125
            .|||:..|||..||||    |:.|||    |.||.|.|:|.||||.||||||.||:|||||.|.|
Mouse    74 KEARKRFLGPLHPSFNLVKTIRGCLL----KTLPADCHERANGRLGISLTRVSDGENVIISHFSS 134

  Fly   126 REEVLQALLCACFIPGFSGILPPRFRGVRYMDGAFSDNLPILD-ENTITVSPFCGESDICPRDQS 189
            ::|::||.:|:.|||.:.|::||..:||||:||..|||||:.: :||||||||.|||||||:|.|
Mouse   135 KDELIQANVCSTFIPVYCGLIPPTLQGVRYVDGGISDNLPLYELKNTITVSPFSGESDICPQDSS 199

  Fly   190 SQLFHLNWANTSIEISRQNINRFVRILFPPRPEFLSKFCQQGFDDALQFLHRNNLINCRRCVAVQ 254
            :.:..|...||||:.:.:|:.|..:.||||.|..|.:.|:||:.|.|:||.||.|:|       |
Mouse   200 TNIHELRVTNTSIQFNLRNLYRLSKALFPPEPMVLREMCKQGYRDGLRFLRRNGLLN-------Q 257

  Fly   255 STFVVSETVAQPQEFDPECR-----------ECKKHRKDALSSNMPQTVLDVIQDYIEQANKGLA 308
            ...:::.....|||.|.|..           :.:.:|||.:..::|..:.:.:.:...:. |.|.
Mouse   258 PNPLLALPPVVPQEEDAEEAAVVEERAGEEDQLQPYRKDRILEHLPARLNEALLEACVEP-KDLM 321

  Fly   309 NWIFKHRGIKL---LSLPATVPMDFLLATISKISALTPKLTKQARVMVE 354
            ..:.....::|   :.:|.|:|::..::...::....|.:.:..|.|.|
Mouse   322 TTLSNMLPVRLATAMMVPYTLPLESAVSFTIRLLEWLPDVPEDIRWMKE 370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bmmNP_001163445.1 Pat_iPLA2 1..245 CDD:132857 130/249 (52%)
Pnpla2NP_001157161.1 Pat_PNPLA2 4..252 CDD:132859 128/246 (52%)
GXGXXG. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 14..19 4/4 (100%)
GXSXG. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 45..49 3/3 (100%)
DGA/G. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 166..168 1/1 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 465..486
Blue background indicates that the domain is not in the aligned region.

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