Protein Alignment bmm and atgl-1

DIOPT Version :10

• Sequence 1: NP_001163445.1
• Gene: bmm / 39611
• FlyBaseID: FBgn0036449
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_741195.1
• Gene: atgl-1 / 175910
• WormBaseID: WBGene00015484
• Length: 751
• Species: Caenorhabditis elegans
• Alignment Length: 646
• Identity: 192/646 - (29%)
• Similarity: 284/646 - (43%)
• Gaps: 191/646 - (29%)

  Fly     1 MNLSFAGCGFLGIYHVGVAVCFKKYAPHLLLEKIGGASAGSLAACCLLCDLPLGSMTSDFFRVVN 65
            |||||:|||||.:||.|||...|:|||.||..||.||||||:.||.|:..:.:...||...:||:
 Worm    11 MNLSFSGCGFLCVYHAGVAAAIKEYAPELLQNKILGASAGSIVACGLITGVCISHATSTILKVVS 75

  Fly    66 EARRYSLGPFSPSFNIQTCLLEGLQKHLPDDAHKRVNGRLHISLTRVYDGKNVIISEFESREEVL 130
            :||..:.||..|.||:...:.:.|:..||.:|::...|||.|||||..|.:||||.|:.|..:::
 Worm    76 QARSRTFGPLHPEFNLLGIVRDELEVILPPNAYEMCTGRLVISLTRWSDHENVIIDEYRSNADLI 140

  Fly   131 QALLCACFIPGFSGILPPRFRGVRYMDGAFSDNLPILDENTITVSPFCGESDICPRD-QSSQLFH 194
            .|::|:||||.:.||.||:||||:|:||..|||.||.||:|:|||||.|||||||.| .|..:..
 Worm   141 DAIMCSCFIPLYCGITPPKFRGVQYIDGGVSDNQPIYDEHTVTVSPFSGESDICPPDWDSGSMLG 205

  Fly   195 LNWANTSIEISRQNINRFVRILFPPRPEFLSKFCQQGFDDALQFLHRNNLINCRRCVAVQ----- 254
            :::..|||..:.:|:.|.:..|:|...:.||:.|.|||.|||:||.:..|..|.||:.:|
 Worm   206 VDFNGTSIRFTTRNMFRLMACLWPRSTDDLSRMCLQGFGDALRFLTKCGLAPCIRCLTIQTIDAN 270

  Fly   255 ------STFVVSET--------VAQPQ---------------EFDPECREC-------------- 276
                  |:...||.        ||.|:               ..:.||..|
 Worm   271 EPAGRVSSECFSENDDAKKVTHVAVPRMKKRASANALNSFRTRGESECETCGDSDIPLEEVNIQS 335

  Fly   277 ------KKHRKDALSSNMPQTVLDVIQDY-----------------------------IEQANKG 306
                  ||..:||:::.  ::|...:..:                             .|.|:..
 Worm   336 FFPSIMKKPFEDAVAAE--RSVFQYMMSFRLVRYATTAMGISKFPFDMALAFVKKLVKCEPADLA 398

  Fly   307 LANWIFK--HRGIKLLSLPATVPM------DFLLATISK-------ISALTP------------- 343
            :....|.  |:.:.::|.|..:.:      ||:|..:.|       .|.|..
 Worm   399 ILTAFFARVHQYLDMVSPPRWIMLKFRGLADFILGEVEKQKSRYTNFSCLVAVAETDSFGSVLAS 463

  Fly   344 -----------KLTKQARVMVEDLILQLNHAMRIRLLNKFTLY----DQPHFDATGLLHSSRLYG 393
                       :|::.|:   :::||......|.:||.|....    .:..||.|.:.
 Worm   464 STMEKEEHKEIELSEDAK---KEMILLRERDRRRKLLKKAGKITPNNSENQFDETSVY------- 518

  Fly   394 PRVSILVDECGATPLEDDVDNFEHVLKMTTHNDALYAYYYTDSNTNKVKVTEIFDFDEITEHDKL 458
                             |||:||||:..|..::|||.::|.|.|    :|.:.|.         |
 Worm   519 -----------------DVDSFEHVIDFTKSHEALYEFHYRDEN----QVMKTFG---------L 553

  Fly   459 ATDLQIYEGSVEDHP----NPHQHSHNTVVSEWNGVESDFFIDAHTPNVED----SKTSAP 511
            .||.|       ..|    :.|||.|...:...:.:       .|.|..::    |..|||
 Worm   554 FTDSQ-------QRPYSSASQHQHHHTKSLGGTSRL-------VHVPEEDEDAPLSAVSAP 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bmm	NP_001163445.1	Pat_iPLA2	1..245	CDD:132857	119/244 (49%)
atgl-1	NP_741195.1	Pat_PNPLA_like	12..252	CDD:132843	118/239 (49%)