Protein Alignment mop and PTPN5

DIOPT Version :9

• Sequence 1: NP_648722.2
• Gene: mop / 39610
• FlyBaseID: FBgn0036448
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: XP_016873923.1
• Gene: PTPN5 / 84867
• HGNCID: 9657
• Length: 719
• Species: Homo sapiens
• Alignment Length: 597
• Identity: 125/597 - (20%)
• Similarity: 203/597 - (34%)
• Gaps: 184/597 - (30%)

  Fly  1229 SYQFSQSGKQQSVGTTDSEIASR----SNTATGFDSPIVSHTKVNMAAKDSTSAIEGNESSNYYS 1289
            :|:.::| ::::....|||..:.    |....|...|||      |.|.|....::.::
Human     2 NYEGARS-ERENHAADDSEGGALDMCCSERLPGLPQPIV------MEALDEAEGLQDSQ------ 53

  Fly  1290 TPYGYLGSVNPQQQPTPAPPS--NSTASIYMQSGASSTAETQTTS------------------SG 1334
                       ::.|.|.|||  :..|......||.|.:.|..:|                  ||
Human    54 -----------REMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSG 107

  Fly  1335 VPYASSAALTKVEPKPEALPPKVTSNVDLLSDLD----IDCSVAVPPPML--------------- 1380
            ..:..|...|.:          |:|.:.||..|:    :|......|.:|
Human   108 YGHIWSQNATNL----------VSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLV 162

  Fly  1381 -------PQPVLQPQVVATPTPPASQVSVPVKVESVAEHAAPATAEIPVAATEGTAQTPVTIPSG 1438
                   |:|       .||.||..      :.:||:...:...:|......|........:|..
Human   163 WHLLRTPPEP-------PTPLPPED------RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPET 214

  Fly  1439 PKCASLDNLSNCSDLSS-------LENFDWDSVSVTHSVSEKQTKASATANGHSSSFAFQSETFT 1496
            |....:.::...:|.:|       |:.....:||:|..:        .|...:...|.:.... .
Human   215 PVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDM--------CTPGCNEEGFGYLMSP-R 270

  Fly  1497 DEKTTKYFQKEVESYEKLL--ENLHVKMLNGKTQLGAKWQELQQKLDKEAAANKRSTTIAKLFPE 1559
            :|...:|    :.|..::|  |.||.|.|: ...|.|::.|:....     .:.:...|..|. .
Human   271 EESAREY----LLSASRVLQAEELHEKALD-PFLLQAEFFEIPMNF-----VDPKEYDIPGLV-R 324

  Fly  1560 KNRSLDCLPYDHARVKL-----DKQTDDYINAAYMKNLSAGCPNFIVAQTPQPNTINDFWSMIWS 1619
            |||....||..|:||.|     |.....||||.|::........:|..|.|..:|:.|||.|:|.
Human   325 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQ 389

  Fly  1620 EKSRTVVCLHTP-----------NELFDPYWPQALDQPTHYDDYTVTCLKVQQLSHCSEYQLKLS 1673
            |        |||           ||....|||   ::...||...:|   ||::.|..:|:|:|.
Human   390 E--------HTPIIVMITNIEEMNEKCTEYWP---EEQVAYDGVEIT---VQKVIHTEDYRLRLI 440

  Fly  1674 MHGADAVLDLSLLQLKQWTKGAPAQLLGVAENALETHRQRCKAANA------PQSPLIMNCLTGS 1732
            .           |:.:.|           .:..|..|:....||.|      |:..:......|.
Human   441 S-----------LKCRDW-----------EDRLLHCHQHLLPAAAAGGCGGHPEDHVPAPSGQGR 483

  Fly  1733 ERSELVAIGVCA 1744
            ...::.|:.|||
Human   484 HDPDMRAVPVCA 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446	2/16 (13%)
		Y_phosphatase	1558..1788	CDD:278528	55/209 (26%)
		PTPc	1559..1745	CDD:238006	55/208 (26%)
PTPN5	XP_016873923.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900