DRSC/TRiP Functional Genomics Resources

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Protein Alignment mop and Brox

DIOPT Version :10

Sequence 1:NP_648722.2 Gene:mop / 39610 FlyBaseID:FBgn0036448 Length:1833 Species:Drosophila melanogaster
Sequence 2:NP_082137.1 Gene:Brox / 71678 MGIID:1918928 Length:411 Species:Mus musculus


Alignment Length:414 Identity:85/414 - (20%)
Similarity:141/414 - (34%) Gaps:126/414 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 ETLRNQA----------MHTTKDGAPVMKRYYCQLHALQNRFPQLADRGIFTFKWKDLYHSAVHE 103
            ||::|.|          :::..|.....|..|.|                 .|||.|.....|..
Mouse    55 ETMKNAADLYFSLLQGFINSVGDSTQESKLRYIQ-----------------NFKWTDTLQGHVPS 102

  Fly   104 V-TDLRFERAAVLFNIAALHTQSGA------SVTRGDVDGMKMACTHFQAAAWAYGELRERYANV 161
            . .|..||..::.||:|..:|:..:      ::|.   |..|......:.||..:..|:|.:   
Mouse   103 AQQDAVFELISMGFNVALWYTKYASRLAGKENITE---DEAKEVHRSLKIAAGIFKHLKESH--- 161

  Fly   162 NGGGDFMTPELLVFQQQ--------------VCFAQAQECILEKSLIDNRKPHIVAKVTAQIVVY 212
                   .|:||...::              .|.|:|||..:.:::.....|.::|.:......:
Mouse   162 -------IPKLLTPAEKGRDLEARLIDAYIIQCQAEAQEVTIARAIELKHAPGLIAALAYDTASF 219

  Fly   213 YGAALAALLTGGDDGPVAQVIDSSVYKLWKKYVRFKINYLTCILYLYQGQHSEEKRQMGERVTLY 277
            |..|         |..::.:..:...| |:||:..|:.:.|...|.|.||......:.||.:.  
Mouse   220 YQKA---------DHTLSSLEPAHSAK-WRKYLHLKMCFYTAYAYCYHGQTLLASDKCGEAIR-- 272

  Fly   278 QASWDKLEEARK-------------ESKGLPDQREINESLSF--TADVVEAKRKNAKNENEFIYH 327
                 .|:||.|             |:||.....:.:..|.|  ...:|:......:.||.|||.
Mouse   273 -----SLQEAEKLYAEAEALCKEYGETKGPGPTAKPSGHLFFRKLGSLVKNTLDKCQRENGFIYF 332

  Fly   328 EAVP-ELSTIAAVQGANLVNGIGFQVSDEEHAGPDIFARLVPMKAH---EASSLYS--------- 379
            :.:| |...:.......||..:.|:              ..||.||   ||.:.:.         
Mouse   333 QKIPTEAPQLELKANYGLVEPVPFE--------------FPPMSAHWTPEALAAFDLTKRPKDDS 383

  Fly   380 -----EEKAKLLRKYGALLEEKDT 398
                 ||..|.: |...:..:|||
Mouse   384 VKPKPEEDVKPV-KEPDIRPQKDT 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mopNP_648722.2 BRO1_HD-PTP_like 2..363 CDD:185762 72/360 (20%)
V_HD-PTP_like 368..702 CDD:185747 13/48 (27%)
Glutenin_hmw <795..1261 CDD:367362
PHA03247 <1329..1443 CDD:223021
PRK12323 <1378..1540 CDD:481241
Y_phosphatase 1558..1788 CDD:459674
BroxNP_082137.1 BRO1_Brox_like 4..356 CDD:185766 71/347 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 375..411 7/33 (21%)
Blue background indicates that the domain is not in the aligned region.

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