DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment mop and PTPN7

DIOPT Version :9

Sequence 1:NP_648722.2 Gene:mop / 39610 FlyBaseID:FBgn0036448 Length:1833 Species:Drosophila melanogaster
Sequence 2:XP_011508121.1 Gene:PTPN7 / 5778 HGNCID:9659 Length:511 Species:Homo sapiens


Alignment Length:510 Identity:103/510 - (20%)
Similarity:161/510 - (31%) Gaps:201/510 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly  1306 PAPPSNSTASIYMQSGASSTAETQTTSSGVPYASSAALTKVEPKPEALPPKV--------TSNVD 1362
            |||    ..|:....|..|.|:..|.|.|      ||:|  :|.||..|.|.        .|||.
Human   100 PAP----HLSMVQAHGGRSRAQPLTLSLG------AAMT--QPPPEKTPAKKHVRLQERRGSNVA 152

  Fly  1363 LLSDLDIDCSVAVPPPMLPQPVLQPQVVATPTPPASQVSVPVKVESVAEHAAPATAEIPVAATEG 1427
            |:  ||:....||.|           :.:..||           ..|..|..            .
Human   153 LM--LDVRSLGAVEP-----------ICSVNTP-----------REVTLHFL------------R 181

  Fly  1428 TAQTPVT------IPSGPKCASLDNLSNCSDLSSLENFDWDSVSVTHSVSEKQTKASATANGHSS 1486
            ||..|:|      .|..||....:.|...|:..|.|:.|                    ..||:|
Human   182 TAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLD--------------------IPGHAS 226

  Fly  1487 SFAFQSETFTDEKTTKYFQKEVESYEKLLENLHVKMLNGKTQLGAKWQELQQKLDKEAAANKRST 1551
            .                     :.|:.:|.|...::..|:.|                       
Human   227 K---------------------DRYKTILPNPQSRVCLGRAQ----------------------- 247

  Fly  1552 TIAKLFPEKNRSLDCLPYDHARVKLDKQTDDYINAAYMKNLSAGCPNFIVAQTPQPNTINDFWSM 1616
                                     .::..|||||.|::........:|..|.|.|||::|||.|
Human   248 -------------------------SQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEM 287

  Fly  1617 IWSEKSRTVV-----------CLHTPNELFDPYWPQALDQPTHYDDYTVTCLKVQQLSHCSEYQL 1670
            :|.|:...:|           |:|        ||      ||..:.|....:::|.:..|.||.:
Human   288 VWQEEVSLIVMLTQLREGKEKCVH--------YW------PTEEETYGPFQIRIQDMKECPEYTV 338

  Fly  1671 K-LSMHGADAVLDLSLLQLKQW-------TKGAPAQLLGVAENALETHRQRCKAANAPQSPLIMN 1727
            : |::...:....:..:....|       :.|...:|:...|.:.||        .|...|::::
Human   339 RQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPET--------AAHPGPIVVH 395

  Fly  1728 CLTGSERSELVAIGVCAIIATQ--NKQPILLNTIDVWSRICAQRQNSLRDSAILE 1780
            |..|..|:.       ..|||:  .:|......:|:...:|..|.:.|.:...||
Human   396 CSAGIGRTG-------CFIATRIGCQQLKARGEVDILGIVCQLRLDRLLERRKLE 443

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mopNP_648722.2 BRO1_HD-PTP_like 2..363 CDD:185762
V_HD-PTP_like 368..702 CDD:185747
ALIX_LYPXL_bnd 421..699 CDD:290660
Med15 808..>1246 CDD:255446
Y_phosphatase 1558..1788 CDD:278528 52/244 (21%)
PTPc 1559..1745 CDD:238006 42/204 (21%)
PTPN7XP_011508121.1 PTPc 201..499 CDD:214550 65/361 (18%)
PTPc 227..499 CDD:238006 57/315 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0789
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.