DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and ptpn22

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_001092890.1	Gene:	ptpn22 / 565606	ZFINID:	ZDB-GENE-060503-458	Length:	887	Species:	Danio rerio

Alignment Length:	339	Identity:	84/339 - (24%)
Similarity:	131/339 - (38%)	Gaps:	71/339 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1515 LENLHVKMLNGKTQ---LGAKWQELQQKLDKEAAANKRSTTIAKLFP--EKNRSLDCLPYDHARV 1574
            |:.:.:|....:|.   ...::.:|:::..|..|.....||.|....  :|||..|.:|:||:||
Zfish    12 LDLIAIKEAEDETAENGFAGEFLKLKRQSTKYRAERTYPTTAADKQDNVKKNRYKDIVPFDHSRV 76

  Fly  1575 KL----DKQTDDYINAAYMKNLSAGCPNFIVAQTPQPNTINDFWSMIWSEKSRTVVCLHTPNEL- 1634
            ||    .|...|||||:::|.:| |...:|..|.|..||:.|||.|||....:.:|.:....|:
Zfish    77 KLSLFTSKNDTDYINASFIKGVS-GSKAYIATQGPLSNTVLDFWRMIWEYNIQVIVMVCREFEMG 140

  Fly  1635 ---FDPYWPQA-------------LDQPTHYDDYTVTCLKV--QQLSHCSEYQLKLSMHGADAVL 1681
               .:.|||::             .:...:..||....|||  :|.|.
Zfish   141 RKKCERYWPESKGDVFVCEAFTILYESDENKGDYLTRTLKVTFKQESR----------------- 188

  Fly  1682 DLSLLQLKQW-TKGAPAQLLGVAENALETHRQRCKAANAPQSPLIMNCLTGSERSELVAIGVCAI 1745
            .|..|....| ..|.|..:..:.|...|   .|....| .:.|:.::|..|..|:.    .:|||
Zfish   189 RLKQLHYVNWPDHGVPDSIPAILELLQE---MRIYQDN-EEIPICIHCSAGCGRTG----ALCAI 245

  Fly  1746 IATQN--KQPILLNTIDVWSRICAQRQNSLRDSAILEQSMQIVLCNAHNVLNKRGIMTSYQMKMA 1808
            ..|.|  |:.|:.....::..:...|          .|...:|.......|..|.|...::..:|
Zfish   246 DYTWNLLKRQIIPEDFSIFELVKGMR----------TQRPSVVQTKEQYELVYRTIKLLFERYLA 300

  Fly  1809 PQVTAKEQQENKDP 1822
                |.|...||.|
Zfish   301 ----ALEAPSNKVP 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	66/257 (26%)
		PTPc	1559..1745	CDD:238006	57/209 (27%)
ptpn22	NP_001092890.1	Y_phosphatase	59..291	CDD:278528	68/267 (25%)
ptpn22	NP_001092890.1	PTPc	61..291	CDD:238006	68/265 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000