Protein Alignment mop and ptprga

DIOPT Version :9

• Sequence 1: NP_648722.2
• Gene: mop / 39610
• FlyBaseID: FBgn0036448
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: NP_001316793.1
• Gene: ptprga / 561197
• ZFINID: ZDB-GENE-101101-4
• Length: 1414
• Species: Danio rerio
• Alignment Length: 1650
• Identity: 298/1650 - (18%)
• Similarity: 523/1650 - (31%)
• Gaps: 537/1650 - (32%)

  Fly   393 LEEKDTQLESYMSSLTLDNLNINEEQANKLPQGIVDRCAALNANKTAISDLVEAMSQLAEITADV 457
            :.::||::......||||..:                  |.::|||::.:..:.::...:....|
Zfish    88 IADQDTKVSMEYQELTLDGFD------------------AESSNKTSMKNTGKTVAIFLKDDYFV 134

  Fly   458 ETNLGEISSMLEAEAKAER-EFQSATGVQRTPNAHITELSREFQKYSEAHARAGESNNTLRKAMS 521
            .      .:.|....|||: ||                             ..|:||.:.....|
Zfish   135 R------GAGLPGRFKAEKVEF-----------------------------HWGQSNGSDGSEHS 164

  Fly   522 LHVNNLKILARPLPEIQQLMPKLSSE---LNTTEIFRDVKLILNKVNEMKAQRAQFHADLRIAIN 583
            ::       .|..|...|:....|.:   |||.  .|:.::|       .|....|..|.:
Zfish   165 IN-------GRRFPVEMQIFMYNSDDFDSLNTA--IREKRVI-------AAMAVFFQVDFK---- 209

  Fly   584 EDDITGKVIAHGGQEGLQALFATELGKHDKIT--------ELLDQNMVAQGNILQALTENYAKAA 640
             |:.....|.|    ||:.:.     .|:|.|        :||..::.:....:.:||     ..
Zfish   210 -DNPAVDPIIH----GLRGVV-----HHEKETFLEPFVLRDLLPSSIGSYYRYIGSLT-----TP 259

  Fly   641 PVLKTLQDVKQKREHF--YSSLAASYDVYEDLLAKSAKGLEFYKKLAGNVQKLLTRFRSARDVQS 703
            |..|.::.:...|...  |..|.|.|.::........|.:|:.:             .:.|.:||
Zfish   260 PCSKVVEWIVFSRPVLLSYKQLEAFYSIFTTEQQDHVKSVEYLR-------------NNFRPLQS 311

  Fly   704 -EERQQRMQSVKAATTPVVSKPIAE---TTPVPAVSSTPKLRD--YLKAKAAMADASNP--AYVP 760
             :.|:....:||.|..|.::.|...   |....|.||.|...:  ::...|.:...|.|  .|.|
Zfish   312 LDNREVFKSAVKDAWLPDLTYPPGNPYGTEASKACSSAPINMNVQHMNKTALVVRWSRPEITYDP 376

  Fly   761 TVRPVPVGSENPTQAACSYATAPPNEPPPPYSLT------QQQYFDPSAAGYTNPMYQQQQQHIA 819
            .:              .||..:        ||.|      ::.||..|         .|:.:.:.
Zfish   377 PI--------------ISYLIS--------YSWTRNDESYEETYFKGS---------DQKLEAVI 410

  Fly   820 PPA-------YKAQA-------SPNSQTLHGALGQMNLQGQSQDNN--QAGMAYNYGYPSGSVPP 868
            .|.       ::.||       |..||::   |.:.|.....:...  :.||
Zfish   411 TPVSPDVLYLFRVQAVCLNDKRSDFSQSM---LFRANTTRIFEGTRIVKTGM------------- 459

  Fly   869 LAYAPPGTVPASSASQGLNIQQPLYVATSGNPVSVSNPSELPSTLQAPFV-----VNPMSNPYQT 928
                 |...|||||...              |:|..:.:...|.|...||     :.|.|:..|.
Zfish   460 -----PTVSPASSADMA--------------PISSGSSTWTSSGLPFSFVSMATGIGPSSSGSQA 505

  Fly   929 AA------------GYSGQAYQQVNAQAQQV-TYPTAPSGSSTGQSAQQPLGYAPSQGPQQ---- 976
            ..            |:||.......:..... ..|::|:.:||.||..:|:.....|....
Zfish   506 TVASVVTSTLLAGLGFSGGVISSFPSSVWPTRPPPSSPAPASTHQSPAKPVVTTAEQASDADTTT 570

  Fly   977 -----------QAGGYPQSQTPQQQVGAYQQQPLSGYAQQLTPQQQTGYSQSQAPQLQAPSYAQN 1030
                       :.||..:.:..::          :|..::...:::.|.|:..    :||...:.
Zfish   571 ATDNDRSDDGGEKGGKGEDEDGEK----------NGEEEEDEDEEKGGESKDS----RAPDDVEK 621

  Fly  1031 QQSTGQAQQQQTGYPQTPQQHLAGYAQSQQQATGYPQSQTSQQQTTGYSQSQTPQQPLAYQQQPS 1095
            |.::..::...|..|.:..:...|..:::....   .|:.|::.|.|..:..|
Zfish   622 QTNSSVSKDPPTAVPDSTAKEKGGRRRTENSTA---PSRVSEENTQGLGEENT------------ 671

  Fly  1096 GYPQQQQQQSLAPQQPSLYPS-QAVQASPQPIPGQQATPPNAG--QPLPYPQQYTDPNAA----P 1153
                    |.:|.::|.:..: .||..:|:..  :|::..|.|  ..||....:|:....    |
Zfish   672 --------QVMASREPEVEENVTAVIETPENT--EQSSKDNRGDRNHLPPFSIHTERTVVSSMYP 726

  Fly  1154 APAPG---------------------------------------VSSVPSPVPVPT------PAP 1173
            .||.|                                       |....||..||.      |.|
Zfish   727 GPAAGRMEWIIPLVVVSALTFLCLILLLAVLVYWRRCFQTAHFYVEDSNSPRVVPNESIPVIPIP 791

  Fly  1174 TSSQAQVPTSPHPSATYTSYSNHPGYSFNPQTGKYEYSSGYQQDTSSLKGSQASQSYQFSQSGKQ 1238
            ...:| :|...........|||:              ..|:..|...::...|........|..
Zfish   792 DDMEA-IPVKHFIKHVSELYSNN--------------QHGFSDDFEEVQRCTADMKITAEHSNH- 840

  Fly  1239 QSVGTTDSEIASRSNTATGFDSPIVSHTKVN---MAAKDSTSAIEGNESSNY---YSTPYGYLGS 1297
                 .|::..:|......:|     |::|.   :|.|||..:...|  :||   |:.|..|:.:
Zfish   841 -----PDNKHKNRYINIIAYD-----HSRVKLRPLAGKDSKHSDYIN--ANYVDGYNKPKAYIAA 893

  Fly  1298 VNPQQQPTPAPPSNSTASIYMQSGASSTAE-----TQTTSSGVPYASSAALTKVEPKPEALPPKV 1357
            ..|                     ..||.|     ....::|:....:..:.|...|.:...|..
Zfish   894 QGP---------------------LKSTFEDFWRMVWEQNTGIIVMITNLVEKGRRKCDQYWPSE 937

  Fly  1358 TSN------VDLLSDLDIDCSVA-----------------VPPPMLPQPVLQPQVVATPTPPASQ 1399
            .|.      |.|.....:.|...                 .......:.|||......|.....:
Zfish   938 NSEEYGNIVVTLKRTKVMACYTLRIFTIRNTKVKKGQKGNTKGRQSERTVLQYHYTQWPDMGVPE 1002

  Fly  1400 VSVPVKVESVAEHAAPATAEIPVAATEGTAQTPVTIPSGPKCAS----------LDNLSNCSDLS 1454
            .::||               :........||||...|....|::          :|::     |.
Zfish  1003 YTLPV---------------LTFVRKSSAAQTPDMGPMLVHCSAGVGRTGTYIVIDSM-----LQ 1047

  Fly  1455 SLENFDWDSVSVTHSVSEKQTKASATANGHSSSFAFQSETFTDE---KTTKYFQKEVESYEKLLE 1516
            .|:  |..:|:|...:...:|:.:.... ....:.|..:...:.   |.|:....::.||   :.
Zfish  1048 QLK--DKGAVNVLGFLKHIRTQRNYLVQ-TEEQYIFIHDALMEAILGKETEVPSSQLHSY---VN 1106

  Fly  1517 NLHVKMLNGKTQLGAKWQELQQKLDKEAAA------------NKRSTTIAKLFPEKNRSLDCLPY 1569
            ::......|||:|     |.|.||..:..|            ||          ||||:...:|.
Zfish  1107 SILTPGPGGKTRL-----EKQFKLVTQCNARFVECFSAQKDCNK----------EKNRNSSVVPS 1156

  Fly  1570 DHARVKL----DKQTDDYINAAYMKNLSAGCPNFIVAQTPQPNTINDFWSMIWSEKSRTVVCLHT 1630
            :.|||.|    ..:..|||||:|:...... ..||:.|.|.|:|..|||.|||...::.:|.|..
Zfish  1157 ERARVGLAPLPGMKGTDYINASYIMGYYRS-NEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPD 1220

  Fly  1631 PNELFDP---YWPQALDQPTHYDDYTVTCLKVQQLSHCSEYQL-----KLSMHGADAVLDLSLLQ 1687
            ...|.:.   ||| :.::..:.:.:|||.:...:|...:|.|:     .|.....|.||::...|
Zfish  1221 NQGLAEDEFVYWP-SREEAMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQ 1284

  Fly  1688 LKQW-TKGAPA----QLLGVAENALETHRQRCKAANAPQSPLIMNCLTGSERSELVAIGVCAIIA 1747
            ..:| ...||.    :|:.|.:....|.          ..|.|::...|:     |:.|:...:.
Zfish  1285 CPKWPNPDAPISSTFELINVIKEEAMTR----------DGPTIVHDEFGA-----VSAGMFCALT 1334

  Fly  1748 TQNKQPILLNTIDVWSRICAQRQNSLRDSAI--------LEQSMQIVLCNAHNVLNKRGIMTSYQ 1804
            |.::|........|:.  .|:..|.:|....        |.::|..::....|..:...:..:..
Zfish  1335 TLSQQLESEGAAGVYQ--VAKMINLMRPGVFTDIEQYQYLYKAMLSLISTKENGSSPMSLDRNGS 1397

  Fly  1805 MKMAPQVTAKEQQENKDPLNELDAL 1829
            |.|:         :..||...|::|
Zfish  1398 MAMS---------DESDPAESLESL 1413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747	55/322 (17%)
		ALIX_LYPXL_bnd	421..699	CDD:290660	48/291 (16%)
		Med15	808..>1246	CDD:255446	85/538 (16%)
		Y_phosphatase	1558..1788	CDD:278528	63/254 (25%)
		PTPc	1559..1745	CDD:238006	55/202 (27%)
ptprga	NP_001316793.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900