Protein Alignment mop and ptpn23b

DIOPT Version :10

• Sequence 1: NP_648722.2
• Gene: mop / 39610
• FlyBaseID: FBgn0036448
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: NP_001038393.1
• Gene: ptpn23b / 560417
• ZFINID: ZDB-GENE-060503-179
• Length: 1229
• Species: Danio rerio
• Alignment Length: 1321
• Identity: 416/1321 - (31%)
• Similarity: 637/1321 - (48%)
• Gaps: 191/1321 - (14%)

  Fly     1 MEAVPRLHMLWFALKSSPEGTSFAALKKYIAEFYHEDPEAYSKEVHALETLRNQAMHTTKD--GA 63
            ||||||:.|:|..||.:.:......:::||...|.|:||.||:.:..||.||...::..:|  |.
Zfish     1 MEAVPRMPMIWLELKEAGDFEFSPTVRQYIEINYGENPENYSEALKRLEQLRQSVVNIPRDFEGC 65

  Fly    64 PVMKRYYCQLHALQNRFPQ-LADRGIFTFKWKDLY--HSAVHEVTDLRFERAAVLFNIAALHTQS 125
            ..:::|..|||.||:|.|. ..........|.|::  .:..||  |:.:|.|.||:|:.|||:..
Zfish    66 NTLRKYCGQLHFLQSRVPMATGQEAALPVTWTDIFTGRNITHE--DINYEHACVLYNLGALHSLL 128

  Fly   126 GASVTRGDVDGMKMACTHFQAAAWAYGELRERYANVNGGGDFMTPELLVFQQQVCFAQAQECILE 190
            ||...|...:|||::|||||.:|.|:..||:.|::.....  |:.:.|.....:..||||||:||
Zfish   129 GAVDNRLSEEGMKVSCTHFQCSAGAFAYLRDHYSHSYSSD--MSSQALSINISLMLAQAQECLLE 191

  Fly   191 KSLIDNRKPHIVAKVTAQIVVYYGAALAALLTGGDDGPVAQVIDSSVYKLWKKYVRFKINYLTCI 255
            |:|:||||.|::||:.||:..||...|..|..       ::.:...:.|.|:|.:..||:|.:.|
Zfish   192 KTLLDNRKSHLIAKICAQVCDYYKDCLRVLEN-------SECVPGRIQKEWRKLINMKISYFSAI 249

  Fly   256 LYLYQGQHSEEKRQMGERVTL--------------YQASWDKLEEARKESKGLPDQREINESLSF 306
            .:|:.|:.|||:::.||.|::              :|.|.|||.||.|:|||.|:  .|.|:|.|
Zfish   250 THLHMGKQSEEQQKYGEAVSVCLCAFSALFDLVAYFQFSLDKLNEAIKQSKGQPE--TIQEALKF 312

  Fly   307 TADVVEAKRKNAKNENEFIYHEAVPELSTIAAVQGANLVNGIGFQVSDEEHAGPDIFARLVPMKA 371
            |.||:..|..:||.:|:|||||:||.|.|:.||:||:||..:...::|:...|||:|::||||..
Zfish   313 TMDVIGGKYNSAKKDNDFIYHESVPSLDTLGAVKGASLVKPLPVSLTDQSVTGPDLFSKLVPMAT 377

  Fly   372 HEASSLYSEEKAKLLRKYGALLEEKDTQLESYMSSLTLDNLNINEEQANKLPQGIVDRCAALNAN 436
            ||||||||||||||||...:.:|:|:..||.:|.||:.|:| ...:....||..::::||.|:..
Zfish   378 HEASSLYSEEKAKLLRDIVSKIEDKNQILEKFMESLSSDSL-YKIDMFKSLPDALLEKCAFLSVR 441

  Fly   437 KTAISDLVEAMSQLAEITADVETNLGEISSMLEAEAKAER---EFQSATGVQRTPNAHITELSRE 498
            ...:.:||:||..|:.:..||.::|.|:.|.||.:...|:   |.....|:...|:. ..::.::
Zfish   442 PDTVKNLVQAMQALSNVYTDVGSSLDEVRSALEEDEAGEKGLIELVGQKGLPAKPSV-FQDIQKD 505

  Fly   499 FQKYSEAHARAGESNNTLRKAMSLHVNNLKILARPLPEIQQLMPKLSSELNTTEIFRDVKLILNK 563
            .:||..||..|..||..|.:||:.|:.||::|...:.|:::.:|:.......|...:.:|.||.|
Zfish   506 LKKYEAAHQTASNSNTELHRAMNQHIPNLRLLQGSVEELRKSLPQPELSQEETVSLQKMKTILGK 570

  Fly   564 VNEMKAQRAQFHADLRIAINEDDITGKVIAHGGQEGLQALFATELGKHDKITELLDQNMVAQGNI 628
            |:||:.||....:.||..|::||||| |:....:...:.|||.:|.|:|::...::||:|||.||
Zfish   571 VDEMRKQRMSLESQLRDLIHKDDITG-VLVTTDRADFKTLFAEQLKKYDQLKGYIEQNLVAQDNI 634

  Fly   629 LQALTENYAKAAPVLKTLQDVKQKREHFYSSLAASYDVYEDLLAKSAKGLEFYKKLAGNVQKLLT 693
            |:||||...:.|||.|||...:|:......:|.||::.||:|:.|:.:|.:||:.|......||.
Zfish   635 LKALTEANVQYAPVRKTLTLTEQQWNTTVQALIASFEAYEELMKKAEEGRDFYQDLDKKTSGLLD 699

  Fly   694 RFRSARDVQSEERQQRMQ--------SVKAATTPVVSKPIA--ETTPVPAVSSTPKLRDYLKAKA 748
            :.:|....:..||...::        |...|..|||.:.:.  .|.|....|.:|.:..:.....
Zfish   700 QTKSYCQTREAERVALLEREIGKGSPSRPTAQKPVVGQKVVGPRTGPSSLESVSPSIASFKNHPL 764

  Fly   749 AMADASNPAYVPTVRPVPVGSENPTQAACSYATAP-PNEPPPPYSLTQQQYFDPSAAGYTNPMYQ 812
            .:....|       ..:|.|.:...|    :.:|| .|:.|                 .|:|..:
Zfish   765 ELQSLPN-------LNLPQGPQRTNQ----FPSAPFLNQIP-----------------ITDPKLR 801

  Fly   813 QQQQHIAPPAYKAQASPNSQTLHGALGQMNLQGQSQDNNQAGMAYNYGYPSGSVPPLAYAPPGTV 877
            ||..|..|........|::......|.....|.:               |:..:.|:..:....|
Zfish   802 QQGAHHLPQNLVPYGQPSTPVQTPGLPPQQFQVR---------------PAAGITPVNQSAFPQV 851

  Fly   878 PASSASQGLNIQQPLY---------VATSGNPVSVS----NPSELPSTL----QAPFVVNPMSNP 925
            ||    ||.|   |.:         .||.|..|...    |.:.:.|||    ||....:.:..|
Zfish   852 PA----QGYN---PAFWQQAHGGHIAATGGYSVPPQMGQINQNSIRSTLPGQPQASLPNSQIGQP 909

  Fly   926 YQTAAGYSGQAYQQVNAQA-----QQVTYPTAPSGSSTGQSAQ--QPLGYAP-SQGPQQQAGGYP 982
            ..|....|..|.|.|..|:     .|..:.|:..|:.:||...  .||...| ..|..||..|.|
Zfish   910 ILTGQPQSSSAQQIVQGQSFTPQPIQSIHSTSQRGAFSGQILPPFSPLQVQPIMPGQTQQQSGLP 974

  Fly   983 QSQTPQQQVGAYQQQPLSGYAQQLTPQQQTGYSQSQAPQLQAPSY-AQNQQSTGQAQQQQTGYPQ 1046
            ....|..   ..|.||..|.:.|||..|..|   :..|....|.: ..||...||..|.:
Zfish   975 SGYQPML---LPQTQPQLGPSGQLTASQPQG---ALIPGQTQPHFNLSNQAHPGQLPQNR----- 1028

  Fly  1047 TPQQHLAGYAQSQQQATGYPQSQ----TSQQQTTGYSQSQT-PQQPLAYQQQPSGYPQQQQQQSL 1106
             |||:: |||     .|.:|.||    ::.||.  :|:||. .|.||....|....|:|..|..:
Zfish  1029 -PQQYM-GYA-----TTSFPSSQPLHISAPQQV--HSRSQLFSQAPLNQNSQVPYGPRQLGQPQM 1084

  Fly  1107 ----APQQPSLYPSQAVQASPQPIPGQQATPP--------NAGQPL--PYPQQYTDPN--AAPAP 1155
                .|.|.::||........||: |||..||        :..||:  |...|...|.  |.|:.
Zfish  1085 PPGPIPPQNNMYPFAPTHMGQQPM-GQQPIPPQFNAMFNGSGRQPMHPPGQSQLLGPQQLAYPSS 1148

  Fly  1156 APGVSSV-PSPVP-------VPTPAP--TSSQAQVPTSPHPSATYTSYSNHPGYSFNPQTGKYEY 1210
            .|.|::| .:|||       :|||:|  .|||:|..|   |::::.:      .:|.|||
Zfish  1149 GPTVAAVMDNPVPPSLANTLIPTPSPLQVSSQSQTTT---PTSSFAT------QNFKPQT----- 1199

  Fly  1211 SSGYQQDTSSLKGSQASQSYQ 1231
            ::....:|::|..:....|.|
Zfish  1200 TNAAPINTNNLDSATVLDSVQ 1220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762	142/379 (37%)
		V_HD-PTP_like	368..702	CDD:185747	122/336 (36%)
		Glutenin_hmw	<795..1261	CDD:367362	129/494 (26%)
		PHA03247	<1329..1443	CDD:223021
		PRK12323	<1378..1540	CDD:481241
		Y_phosphatase	1558..1788	CDD:459674
ptpn23b	NP_001038393.1	BRO1_HD-PTP_like	2..369	CDD:185762	142/379 (37%)
		V_HD-PTP_like	374..708	CDD:185747	122/336 (36%)
		Med15	733..>1140	CDD:312941	117/477 (25%)
		PABP-1234	<1105..1222	CDD:130689	38/131 (29%)