Protein Alignment mop and ptprz1b

DIOPT Version :10

• Sequence 1: NP_648722.2
• Gene: mop / 39610
• FlyBaseID: FBgn0036448
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: XP_073803012.1
• Gene: ptprz1b / 553019
• ZFINID: ZDB-GENE-050506-100
• Length: 1457
• Species: Danio rerio
• Alignment Length: 1507
• Identity: 295/1507 - (19%)
• Similarity: 480/1507 - (31%)
• Gaps: 474/1507 - (31%)

  Fly   549 NTTEIFRDVKLILNKVN------------EMKAQRAQFHADLRIAINEDDITGKVIAHGGQEGLQ 601
            ::|.|..|.|.::..:|            ..|..|..||.....|.::          |.:..|.
Zfish    93 DSTTITNDGKTVVIGLNSEYFISGGGLRSRFKVGRITFHWGRCNATSD----------GSEHSLN 147

  Fly   602 A-LFATELGKH---DKITELLDQNMVAQGNI------LQALTENYAKAAPVLKTLQDV----KQK 652
            . .|..|:..:   |...|.:|:.|.:.|.|      .||..|:....|.:::.:.:|    |..
Zfish   148 GNRFPLEMQIYCFDDLEFESIDEAMSSGGKIAAVAVLFQASIEDNQDYAAIIEGVNNVSRFGKSS 212

  Fly   653 REHFYSSLA------ASYDVYEDLLA--KSAKGLEF--YKKLAGNVQKLLTRFRSARDVQS---- 703
            ....:|.||      ..|.:|...|.  ..::.:|:  :|...|..:..|..|.....:|.
Zfish   213 AVEEFSLLALLPENTEKYFMYNGSLTAPPCSENVEWIVFKNTVGISETQLEVFCEVMTMQQAGYA 277

  Fly   704 -----------EERQQRMQSVKAATTPVVSKPIAETTPVPAVSSTPKLRDYLKAKAAMADASN-- 755
                       |::||.|..|.::.|.      .|..|.|..||.|        :...||:.|
Zfish   278 MLTDYLQNNYREQQQQFMGQVFSSYTG------TEEVPAPMCSSEP--------QNVQADSQNFT 328

  Fly   756 PAYVPTVRPVPVGSENPTQAACSYATAPPNEPPPPYSLTQQQYF---DPSAAGYTNPMYQQQQQH 817
            ...|...||..|......:.:.:|.......||      :|||.   |.......:.:
Zfish   329 GIVVTWERPRAVYDTVIERYSVTYQRLQGQNPP------KQQYLTDGDQDVGAIIHNL------- 380

  Fly   818 IAPPAYKAQASPNSQTLHGALGQMNLQ-----------------GQSQDNNQAGMAYNYGYPSGS 865
            :|..:|..|..  :..::|..|:|:.|                 |...::.:    ||..:.|.
Zfish   381 LANSSYVVQVV--ALCMNGLTGKMSDQVIVDMPFEDPVNEPDPYGDLAESEE----YNEEHTSA- 438

  Fly   866 VPPLAYAPPGTV----PASSASQGLNIQQP--LYVATSGNPVSVSNPSELPSTLQAPFVVN---- 920
              |.:..|||..    ..||.|...:..||  |:..:...|::|.......|:|..|.|.|
Zfish   439 --PSSKPPPGRFLIRDSGSSISITTSTDQPGFLFPVSRTTPITVRRKITEESSLSQPPVQNKSRK 501

  Fly   921 ------------------PMSNPYQTAAGYSGQAYQQVNAQAQQVTYPTAPSGSSTGQSAQQPLG 967
                              |.||...|...|.    ..:|:....:| ||..:.....|:.::
Zfish   502 NETKRPANRLLPDDSGHFPQSNTVVTDVYYE----DVLNSSTTNIT-PTINNNLLIDQNTEK--- 558

  Fly   968 YAPSQGPQQQAGGYPQSQTPQQQVGAYQQQPLSGYAQQLTP------QQQTGY------------ 1014
             |.:..|:|.|.   :|.|.....|:.....:...:|...|      ...|.:
Zfish   559 -ASTSPPKQPAN---ESSTANATTGSSLSASMKIISQTTQPLFNDVFVTATSFNNERVLMVSDAT 619

  Fly  1015 ----SQSQAPQL--------QAPSYAQNQQS-TGQA----------------------------Q 1038
                |.:::|.:        ..||..|.:.| :|.|                            :
Zfish   620 SLYESSTRSPTIILEEGSAHFPPSDGQGEFSGSGSAIFLEELDREWELEQTRMAPKNADPRKTQE 684

  Fly  1039 QQQTGYPQTPQQHLAGYAQSQQQA--TGYPQSQT-------SQQQTTGYSQ-----SQTPQQPLA 1089
            :...|.|.|      .:.:|:::|  |..||:|.       |.:..:|..|     |||...|:
Zfish   685 ENHEGLPST------FFFESEREASSTYKPQNQDFLSWVTWSAESDSGSGQGGSMISQTEDIPI- 742

  Fly  1090 YQQQPSGYPQQQQQQSLAP----QQPSLYPSQAVQASPQP---IPGQQATPPNAGQPLPYPQQYT 1147
                          |.:.|    |:.:  .::|..:||:.   :.|...|...|..||......|
Zfish   743 --------------QLIIPKLNIQEEN--HAEASNSSPESRVGMVGGTETEKRAVVPLAIVSTLT 791

  Fly  1148 --------------------------DPNAAPAPAPGVSSVPSPVPVPTPAPTSSQAQVPTSPHP 1186
                                      |.|:|.|     .|.||   .|...||.....:|.....
Zfish   792 VLCLVVLVGILIYWRRCFQTAHFYVEDTNSARA-----ISAPS---TPLLLPTEDNEALPVKDFV 848

  Fly  1187 SATYTSYSNHPGYSFNPQTGKYEYSSGYQQDTSSLKGSQASQSYQFSQSGKQQSVGTT------- 1244
            ......::||.                :.::...||     :||:..| |....:|.|
Zfish   849 KHVADLHANHK----------------FSKEFEILK-----ESYEEIQ-GCTADMGITTDSSNHP 891

  Fly  1245 DSEIASRSNTATGFDSPIVSHTKVNMAAKDSTSAIEGNE-SSNY---YSTPYGYLGSVNPQQQPT 1305
            |::..:|......:|     |::|.::.........|:. ::||   ::.|..|:.:    |.|.
Zfish   892 DNKSKNRYINILAYD-----HSRVKLSQNSDKDGKTGDYINANYVDGFNQPKAYIAA----QGPL 947

  Fly  1306 PAPPSNSTASIYMQSGASSTAETQTTSSG--------------------VPYASSAALTKVEPKP 1350
            .....:....|:.|:.......|.....|                    |...||..|.....:.
Zfish   948 KGSLEDFWRMIWEQNVGVIVMITNLVEKGRRKCDQYWPLENQEDYGCFLVTLKSSRTLAYYTLRT 1012

  Fly  1351 EALPPKVTSNVDLLSDLDIDCSVAVPPPMLPQPVLQPQVVATPTPPASQVSVP----VKVESVAE 1411
            ..|     .||.:........|       ..:.||.......|.....:.::|    ::..|.|.
Zfish  1013 FTL-----RNVQIKKGSQKGRS-------QERTVLHFHYTQWPDMGVPEYTLPLLSFIRTSSQAR 1065

  Fly  1412 HAAPATAEIPVAATEGTAQTPVTIPSGPKCASLDNLSNCSD------------LSSLENFDWDSV 1464
            .|......:..:|..|...|.:.|.|..|....:|..|...            :.:.|.:.:...
Zfish  1066 TAEMGPVVVHCSAGVGRTGTYIVIDSMLKQIKEENTVNIMGFLKHIRTQRNYLVQTEEQYVFIHD 1130

  Fly  1465 SVTHSVSEKQTKASATANGHSSSFAFQSETFTDEKTTKYFQKEVESYEKLLENLHVKMLNGKTQL 1529
            ::..::..|:|..|::.                          :.:|   :..|......|||.|
Zfish  1131 ALVEAIRSKETLVSSSL--------------------------IHTY---VSGLLTPGPAGKTPL 1166

  Fly  1530 GAKWQELQQKLDKEAAANKR--STTIAKLFPEKNRSLDCLPYDHARVKLDK---QTDDYINAAYM 1589
                 |.|.||..::.|.:.  :|.:.:....|||:...:|.:.:||.|..   ::.|||||:|:
Zfish  1167 -----EKQFKLVSQSCAKQSDYTTALKESNVSKNRTACLMPVERSRVSLSAAAGESSDYINASYL 1226

  Fly  1590 KNLSAGCPNFIVAQTPQPNTINDFWSMIWSEKSRTVVCL----HTPNELFDPYWPQALDQPTHYD 1650
            ...... ..|||.|.|.||||:|||.|||...::.:|.|    :..:|....||| ..|:|...:
Zfish  1227 LGFHQS-REFIVTQNPLPNTIHDFWRMIWDHNTQIIVSLPDTHNMSSEAECVYWP-TKDEPISCE 1289

  Fly  1651 DYTVTCLKVQQLSHCSEYQLKLSMHGADAVLDLSLLQLKQWTKGAPAQLLGVAENALETHRQRCK 1715
            .:||        |...|..|.||......|....|..||.             :..||.|:.:..
Zfish  1290 TFTV--------SFRDEDSLNLSNEEPVLVQHFILEALKD-------------DYVLEVHQFQSP 1333

  Fly  1716 AANAPQSPLIMNCL-------TGSERSE---LVAIG--------VCAIIATQNKQPILLNTIDVW 1762
            ....|.|| |.||.       ..|.|.|   |:..|        .||::...| |....|::||:
Zfish  1334 RWPDPDSP-ISNCFELINIIREESSRREGPVLIHDGCGGSSAGLFCALVTLVN-QLDEENSVDVY 1396

  Fly  1763 SRICAQRQNSLR 1774
            .  .|:..|.:|
Zfish  1397 Q--TARMINLMR 1406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747	37/188 (20%)
		Glutenin_hmw	<795..1261	CDD:367362	112/626 (18%)
		PHA03247	<1329..1443	CDD:223021	22/137 (16%)
		PRK12323	<1378..1540	CDD:481241	27/177 (15%)
		Y_phosphatase	1558..1788	CDD:459674	71/242 (29%)
ptprz1b	XP_073803012.1	None