DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and Ptp61F

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	391	Identity:	88/391 - (22%)
Similarity:	150/391 - (38%)	Gaps:	115/391 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1470 VSEKQTKASATANGHSSSFAFQSETFTDEKTTKYFQKEVESYEKLLENLHVKMLNGKTQLGAKW- 1533
            :||::|..|.:|                  .....|.|.|..:|                |.:|
  Fly     1 MSEQKTSGSGSA------------------AAARLQIEAEYKDK----------------GPQWH 31

  Fly  1534 ---QELQQKLDKEAAANKRSTTIAKLFPEK--NRSLDCLPYDHARVKLDKQTDDYINAAYMKNLS 1593
               :|:.:..|:||...:.||:.::....:  ||..|..||||:|:.|.:.:.|||||..:: |.
  Fly    32 RFYKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVLKRGSVDYINANLVQ-LE 95

  Fly  1594 AGCPNFIVAQTPQPNTINDFWSMIWSEKSRTVVCLHTPNELFDP-------YWP------QALDQ 1645
            .....:|:.|.|..:|:..||.|:|.:|||.|:.|   |:|.:.       |||      :||..
  Fly    96 RAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLML---NKLMEKKQIKCHLYWPNEMGADKALKL 157

  Fly  1646 PTHYDDYTVTCLKVQQLSHCSEYQLKLSMHGADAVLDLSLLQLKQ--------WTK-GAPAQLLG 1701
            |  :...||..::::...:......||:        ||...|.::        |.. |.|:
  Fly   158 P--HVKLTVELVRLETYQNFVRRWFKLT--------DLETQQSREVMQFHYTTWPDFGIPS---- 208

  Fly  1702 VAENALETHRQRCK---AANAPQSPLIMNCLTGSERSELVAIGVCAIIATQNKQPILLNTIDVWS 1763
             :.||.....|:.:   ..:....|.:::|..|..||....:..|.::           .||.:.
  Fly   209 -SPNAFLKFLQQVRDSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCLV-----------LIDKYG 261

  Fly  1764 RICAQRQNSLRDSAILEQSMQIVLCNAHNVLNKRG-IMTSYQMKMAPQVTAKEQQENKDPLNELD 1827
                            |.::..|||...:.  :.| |.|:.|:..:.|...:..::..|| ..||
  Fly   262 ----------------ECNVSKVLCELRSY--RMGLIQTADQLDFSYQAIIEGIKKLHDP-TFLD 307

  Fly  1828 A 1828
            |
  Fly   308 A 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	59/256 (23%)
		PTPc	1559..1745	CDD:238006	55/212 (26%)
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	72/308 (23%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	66/280 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900