DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and Y62F5A.10

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_001022486.1	Gene:	Y62F5A.10 / 3564988	WormBaseID:	WBGene00013388	Length:	437	Species:	Caenorhabditis elegans

Alignment Length:	396	Identity:	78/396 - (19%)
Similarity:	158/396 - (39%)	Gaps:	55/396 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1440 KCASLDNL---SNCSDLSSLENFDWDSVSVTHSVSEKQTKASATANGHSSSFAFQSETFTDEKTT 1501
            |.||.|:|   .:.:|::|..|....:||.| :|..:|..|.|.::....:.|.||.|.|.::
Worm    50 KTASNDDLRKHGSTNDVTSDGNPALITVSDT-NVFHEQLTAPARSSTPLKTPAAQSPTPTADR-- 111

  Fly  1502 KYFQKEVESYEKLLENLHVKMLNGKTQLGAKWQELQ------QKLDKE------------AAANK 1548
                       ::.|.:.|......::...||:...      .|||..            ..||.
Worm   112 -----------QIGEPVPVAPTPALSEAPVKWKAEDVAVAYIGKLDASQTRPEYIDVCVATKANI 165

  Fly  1549 RSTTIAKLFPEKNRSLDCLP-YDHARVKLDKQTDDYINAAYMKNLSAGCPNFIVAQTPQPNTIND 1612
            .:.|:.|....||:: |..| .|...||...:.|.|:|.:.:.......| .::.|.|:.....:
Worm   166 ENCTVWKKNLAKNQT-DVYPILDATLVKDPAKPDSYVNMSSVIVPHCSYP-ILMGQIPKRGLEEE 228

  Fly  1613 FWSMIWSEKSRTVVCLH----TPNELFDPYWPQALDQPTHYDDYTVTCLKVQQL-SHCSEYQLKL 1672
            ||...::|:   ||.::    :.:|.:| ::|:......:|.:..|...||::: ...|.|.:::
Worm   229 FWRAAYNEQ---VVMMYVLVGSEDEKYD-FFPKTTGSFLYYGEMFVNVRKVEKMDEERSRYTIEV 289

  Fly  1673 SMHGADAVLDLSLLQLKQWTK-GAPAQLLGVAENALETHRQRCKAANAPQSPLIMNCLTGSERSE 1736
            ..:|....:.:::.....|.. |.|.:......:.::. ....|::|..:..|:::.........
Worm   290 LPNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDV-MNFVKSSNGSEKLLVVSKNGCGRAGF 353

  Fly  1737 LVAIGVCAIIATQNKQPILLNTIDVWSRICAQRQNSLRDSAILEQSMQIVLCNAHNVLNKRGIMT 1801
            .:.:|........|.:|   ...::...|.:||.|::..   ::|...:.||..:.:..|..:..
Worm   354 FITLGAAFCCLNDNSEP---RIGEIVKAIRSQRPNAVES---IKQYASLYLCLLYYIKKKITVPE 412

  Fly  1802 SYQMKM 1807
            ..|.|:
Worm   413 GLQQKV 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	42/236 (18%)
		PTPc	1559..1745	CDD:238006	35/192 (18%)
Y62F5A.10	NP_001022486.1	PTPc	162..402	CDD:214550	48/252 (19%)
Y62F5A.10	NP_001022486.1	PTPc	177..402	CDD:304379	44/237 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900