Protein Alignment mop and Rhpn2

DIOPT Version :9

• Sequence 1: NP_648722.2
• Gene: mop / 39610
• FlyBaseID: FBgn0036448
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: NP_001100975.1
• Gene: Rhpn2 / 308516
• RGDID: 1308366
• Length: 686
• Species: Rattus norvegicus
• Alignment Length: 578
• Identity: 117/578 - (20%)
• Similarity: 201/578 - (34%)
• Gaps: 128/578 - (22%)

  Fly    14 LKSSPEGTSFAALKKYIAEFYHEDPEAYSKEVHALETLRNQAMHTTKD--GAPVMKRYYCQLHAL 76
            ||.:.|.......|.:|.|.|.||...|..::..|..||......::|  |..::..|:.||..:
  Rat   117 LKETKEVDFSIVFKDFILEHYSEDSYLYEDDIADLMDLRQACRTPSRDEAGVELLMSYFIQLGFV 181

  Fly    77 QNR-FPQLADRGIFTFKWKDLYHSAVHEVTDLRFERAAVLFNIAALHTQSGASVTRGDVDGMKMA 140
            ::| ||.....|:. |.|.|.:.........|..|:|::||||.||:||.|....|....|::.|
  Rat   182 ESRFFPPTRHMGLL-FTWYDSFTGVPVSQQTLLLEKASILFNIGALYTQIGTRCNRQTEAGLESA 245

  Fly   141 CTHFQAAAWAYGELRERYANVNGGGDFMTPELLVFQQQVCFAQAQECILEK-SLIDNRKPHIVAK 204
            ...||.||.....|:|.:.:.....  |:|.:|....::..|||||.:.|| .|:..:....|..
  Rat   246 VDAFQRAAGVLNYLKETFTHTPSYD--MSPAMLSVLVKMMLAQAQESVFEKICLLGIQNEFFVLV 308

  Fly   205 VTAQIVVYYGAALAALLTGGDDGPVAQVIDSSVYKLWKKYVRFKINYLTCILYLYQG-------- 261
            ..||......||...|.......||.:.|..|    |......|..:...:.:.:..
  Rat   309 KVAQEAAKVAAAYRQLHAAMSQEPVKENIPYS----WASVAYVKAYHYGALAHYFAATLLIDHQL 369

  Fly   262 ------QHSEE------------------KRQMGERVTLYQASWDKLEEARKES-------KGLP 295
                  .|.|:                  .:..|:||.|.:....:..:..|||       |.|.
  Rat   370 KPGADEDHQEKCLSQLYDRMPEGMTPLATLKNDGQRVLLGKGHLHRAIDYHKESLREANLCKKLR 434

  Fly   296 DQREINESLSFTADVVEAKRKNAKNENEFI------------------------------YHEAV 330
            |.:.:.:.||......:.|....:.:::.:                              :.:.:
  Rat   435 DIQVLRDVLSAAHQRTQLKYTQHQQDDDLLNLIDAPDVLPKTEREVKITFPDFSKVTVTDFFQKL 499

  Fly   331 PELSTIAAVQGANLVNGIGFQVSD------------------EEH-----AGPDIFARLVPMKAH 372
            ..||..:|.:..:...||.|:|.:                  :.|     ||......:|.::..
  Rat   500 GPLSVFSASKRWSPPRGIHFRVEEGDLGFTLRGNTPVQVHFLDPHCSASLAGAKEGDYIVSIQGL 564

  Fly   373 EASSLYSEEKAKLLRKYGALLEEKDTQLESYMSSLTLDNLNINEEQANKLPQGIVDRCAALNANK 437
            :...|...|..|||:.:|.  ||.:.::.|.:.|.:                .:.::||..:...
  Rat   565 DCKWLTVSEVMKLLKSFGG--EEVEMKVVSLLDSTS----------------SMHNKCATYSVGM 611

  Fly   438 TAISDLVEAMSQLAEITADVETNLGEISSMLEAEAKAEREFQSAT------GVQRTPN 489
            .....:: .:|...:..||....:.:..|.|.......|:..::|      |:.|..|
  Rat   612 QKTYSMI-CLSMDDDDKADKTKKISKKPSFLSWSTSKNRQKSASTLCLPNVGLARPQN 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762	94/444 (21%)
		V_HD-PTP_like	368..702	CDD:185747	22/128 (17%)
		ALIX_LYPXL_bnd	421..699	CDD:290660	12/75 (16%)
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528
		PTPc	1559..1745	CDD:238006
Rhpn2	NP_001100975.1	HR1_Rhophilin-2	27..108	CDD:212024
		BRO1_Alix_like	112..496	CDD:301330	84/385 (22%)
		PDZ_signaling	520..591	CDD:238492	13/72 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2220
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810