DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and ptpn1

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_001300614.1	Gene:	ptpn1 / 30081	ZFINID:	ZDB-GENE-980605-23	Length:	433	Species:	Danio rerio

Alignment Length:	316	Identity:	73/316 - (23%)
Similarity:	138/316 - (43%)	Gaps:	37/316 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1533 WQELQQKLDKEAAANKRSTTIAKLFPE---KNRSLDCLPYDHARVKLDKQTDDYINAAYMKNLSA 1594
            |.::.|::.::  ::.....|||| ||   :||..|..|:||:|:.|....:|||||:.: ::..
Zfish    14 WNDVYQEIRQQ--SSDLPCKIAKL-PENRSRNRYRDVSPFDHSRICLQIGCNDYINASLI-SVEE 74

  Fly  1595 GCPNFIVAQTPQPNTINDFWSMIWSEKSRTVVCLHTPNELFD-------PYWPQALDQPTHYDD- 1651
            ....:|:.|.|.|||...||.|:|.::||.||.|   |.:.:       .||||..::...::|
Zfish    75 AQRKYILTQGPLPNTCGHFWEMVWEQRSRGVVML---NRVIEKGSVKCAQYWPQREEREAVFEDT 136

  Fly  1652 -YTVTCLKVQQLSHCSEYQLKLSMHGADAVLDLSLLQLKQW----TKGAPAQLLGVAENALETHR 1711
             :.:|.:.....|:.:..||:|.........::.......|    ...:||..|.......|:
Zfish   137 NFRLTLISEDVKSYYTVRQLELENLSTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRES-- 199

  Fly  1712 QRCKAANAPQ-SPLIMNCLTGSERS-ELVAIGVCAIIATQNKQPILLNTIDVWSRICAQRQNSLR 1774
                ...:|: .|::::|..|..|| ....:..|.::.:|.|.|..:...:|...:...|...::
Zfish   200 ----GCLSPELGPVVVHCSAGIGRSGTFCLVDTCLLLMSQRKDPSSVRIQEVLLEMRRYRMGLIQ 260

  Fly  1775 DSAILEQSMQIVLCNAHNVLNKRGIMTSY-----QMKMAPQVTAKEQQENK-DPLN 1824
            .:..|..|....:..|..::....:..|:     :..:.|::|...:...: ||.|
Zfish   261 TADQLRFSYLAFIEGAKYIMGDTSVQESWKELSNEEDLPPELTPPPRPPPRIDPPN 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	60/247 (24%)
		PTPc	1559..1745	CDD:238006	52/203 (26%)
ptpn1	NP_001300614.1	PTPc	1..274	CDD:214550	66/272 (24%)
ptpn1	NP_001300614.1	PTPc	41..274	CDD:238006	58/242 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900