DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and Ptpn1

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	XP_038960209.1	Gene:	Ptpn1 / 24697	RGDID:	61965	Length:	451	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	69/256 - (26%)
Similarity:	118/256 - (46%)	Gaps:	41/256 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1553 IAKLFPEKNRS--LDCLPYDHARVKLDKQTDDYINAAYMKNLSAGCPNFIVAQTPQPNTINDFWS 1615
            ||||...|||:  .|..|:||:|:||.::.:|||||:.:| :.....::|:.|.|.|||...||.
  Rat    53 IAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIK-MEEAQRSYILTQGPLPNTCGHFWE 116

  Fly  1616 MIWSEKSRTVVCLHTPNELFD-------PYWPQALDQPTHYDD--YTVTCLKVQQLSHCSEYQLK 1671
            |:|.:|||.||.|   |.:.:       .||||..::...:||  ..:|.:.....|:.:..||:
  Rat   117 MVWEQKSRGVVML---NRIMEKGSLKCAQYWPQKEEKEMVFDDTNLKLTLISEDVKSYYTVRQLE 178

  Fly  1672 LSMHGADAVLDLSLLQLKQW----TKGAPAQLLGVAENALETHRQRCKAANAPQ-SPLIMNCLTG 1731
            |.........::.......|    ...:||..|.......|:      .:.:|: .|::::|..|
  Rat   179 LENLATQEAREILHFHYTTWPDFGVPESPASFLNFLFKVRES------GSLSPEHGPIVVHCSAG 237

  Fly  1732 SERSELVAIG-VCAIIATQNKQPILLNTIDVWSRICAQRQ---------NSLRDS--AILE 1780
            ..||....:. .|.::..:.|.|   :::|:...:...|:         :.||.|  |::|
  Rat   238 IGRSGTFCLADTCLLLMDKRKDP---SSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIE 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	65/251 (26%)
		PTPc	1559..1745	CDD:238006	56/202 (28%)
Ptpn1	XP_038960209.1	PTPc-N1	38..311	CDD:350456	69/256 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900