DRSC/TRiP Functional Genomics Resources

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Protein Alignment mop and Ptpn2

DIOPT Version :9

Sequence 1:NP_648722.2 Gene:mop / 39610 FlyBaseID:FBgn0036448 Length:1833 Species:Drosophila melanogaster
Sequence 2:NP_001120649.1 Gene:Ptpn2 / 19255 MGIID:97806 Length:406 Species:Mus musculus


Alignment Length:248 Identity:65/248 - (26%)
Similarity:105/248 - (42%) Gaps:36/248 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly  1532 KWQELQQKLDKEAAANKRSTTIAKLFPE---KNRSLDCLPYDHARVKLDKQTDDYINAAYMKNLS 1593
            :||.|..::..|  ::.....:|| |||   :||..|..||||:||||....:|||||: :.::.
Mouse    17 RWQPLYLEIRNE--SHDYPHRVAK-FPENRNRNRYRDVSPYDHSRVKLQSTENDYINAS-LVDIE 77

  Fly  1594 AGCPNFIVAQTPQPNTINDFWSMIWSEKSRTVVCLHTPNELFD----PYWPQALDQPTHYDD--- 1651
            ....::|:.|.|.|||...||.|:|.:|::.||.|:...|...    .|||.        ||   
Mouse    78 EAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRTVEKESVKCAQYWPT--------DDREM 134

  Fly  1652 ------YTVTCLKVQQLSHCSEYQLKLSMHGADAVLDLSLLQLKQWTK-GAPAQLLGVAENALET 1709
                  ::|..|.....|:.:.:.|:|..........:|......|.. |.|...........:.
Mouse   135 VFKETGFSVKLLSEDVKSYYTVHLLQLENINTGETRTISHFHYTTWPDFGVPESPASFLNFLFKV 199

  Fly  1710 HRQRCKAANAPQSPLIMNCLTGSERSELVA-IGVCAIIATQ----NKQPILLN 1757
            ....|...:  ..|.:::|..|..||...: :..|.::..:    |.:.:|||
Mouse   200 RESGCLTPD--HGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGEDVNVKQLLLN 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mopNP_648722.2 BRO1_HD-PTP_like 2..363 CDD:185762
V_HD-PTP_like 368..702 CDD:185747
ALIX_LYPXL_bnd 421..699 CDD:290660
Med15 808..>1246 CDD:255446
Y_phosphatase 1558..1788 CDD:278528 58/222 (26%)
PTPc 1559..1745 CDD:238006 53/203 (26%)
Ptpn2NP_001120649.1 PTPc 5..274 CDD:214550 65/248 (26%)
PTPc 45..274 CDD:238006 56/217 (26%)
Substrate binding. /evidence=ECO:0000250 216..222 2/5 (40%)
Endoplasmic reticulum location. /evidence=ECO:0000250 341..406
Mediates interaction with STX17. /evidence=ECO:0000250 371..406
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0789
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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