DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and ZK484.7

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_491758.1	Gene:	ZK484.7 / 191327	WormBaseID:	WBGene00022753	Length:	344	Species:	Caenorhabditis elegans

Alignment Length:	377	Identity:	82/377 - (21%)
Similarity:	136/377 - (36%)	Gaps:	88/377 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1470 VSEKQTKASATANGHSSSFAFQSETFTDEKTTKYFQKEVESYEKLLENLHVKMLNGKTQLGAKWQ 1534
            :.:::||.|...:...|.......|..::||   .:|::           ||.:....:.|
Worm     5 IQKRRTKKSTQKSKEVSQRTVDEGTTAEKKT---HRKQI-----------VKFVKNALEKG---- 51

  Fly  1535 ELQQKLDKEAAANKRSTTIAKL--FPE-----KNRSLD--CLPYDHARVKLDKQ-TDDYINAAYM 1589
              ...|..|.||.||.....|:  |.|     |||..|  ||  ||.||||... ..|||:|.::
Worm    52 --PAGLRAEFAAMKRFNDFEKMKAFKEAQEHGKNRYKDVGCL--DHNRVKLHPPWPHDYIHANFV 112

  Fly  1590 KNLSAGCPNFIVAQTPQPNTINDFWSMIWSEKSRTVVCL-----HTPNELFDPYWPQALDQPTHY 1649
            ...| ....||..|.|...:..|||.|...||..::..|     ....:..|.:  ...|:|.
Worm   113 STPS-NPRRFICTQAPLDKSCADFWYMCLQEKVDSIFMLCNIMEKGAKKCCDYF--ACKDKPV-- 172

  Fly  1650 DDYTVTCLKVQQLSHCSEYQLKLSMHG-------ADAVLDLSLLQLK---------------QW- 1691
                   |:.::..|  :..:|....|       .||.:..::..::               .|
Worm   173 -------LEFEEKGH--KIIVKFESTGKMKFEKNTDAKITETVFTVEGPGGLAQKVTQYHWIDWP 228

  Fly  1692 TKGAPAQLLGVAENALETHRQRCKAANAPQSPLIMNCLTGSERSELVAIGVCAIIATQNKQPILL 1756
            .:|.|...:.:.|...:|...:        .|.:::|..|..|:..|.:....:......|.| .
Worm   229 DRGVPTADMAIVELLAKTRPSK--------GPTVVHCSAGIGRTGSVVMIEYILDQLLGGQQI-E 284

  Fly  1757 NTIDVWSRICAQRQNSLRDSAILEQSMQIVLCNAHNVLNKRGIMTSYQMKMA 1808
            .|..:..:|..||.||::.........|::|   :..|:|:  |....:|:|
Worm   285 ETDKILQKIREQRNNSIQTDQQYLFVHQVIL---NYCLDKK--MFDVDVKLA 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	57/265 (22%)
		PTPc	1559..1745	CDD:238006	48/221 (22%)
ZK484.7	NP_491758.1	Y_phosphatase	80..316	CDD:278528	57/263 (22%)
ZK484.7	NP_491758.1	PTPc	81..316	CDD:238006	57/262 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900