DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and Y116A8C.37

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_503038.1	Gene:	Y116A8C.37 / 191006	WormBaseID:	WBGene00013810	Length:	298	Species:	Caenorhabditis elegans

Alignment Length:	272	Identity:	55/272 - (20%)
Similarity:	101/272 - (37%)	Gaps:	55/272 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1506 KEVESYEKLLENLHVKMLNGKTQLGAKWQELQQK--LDKEAAANKR------------STTIAKL 1556
            |:||...|:::...:....|:.....|.:..::|  :|||..:.:.            :|.:...
Worm    22 KKVEELGKVVDRKEMDSPLGRLYEEKKEERKEEKKEVDKEPWSGEEPAKRMVANGFFTTTNVGGT 86

  Fly  1557 FPE-------------------KNRSLDCLPYDHARVKLDKQTDDYINAAYMKNLSAGCPNF--- 1599
            |.:                   |.|:.||...:...|||....:.:|.||.:.     .|:|
Worm    87 FKQTDNFKTPMDSCPSFKNNMHKIRAPDCPIPEEKLVKLANGPESFICAAKIT-----VPDFNRT 146

  Fly  1600 -IVAQTP----QPNTINDFWSMIWSEKSRTVVCLHTPNEL-FDPYWPQALDQPTHYDDYTVTCLK 1658
             |:.|.|    .|:|. |||.||..|...:||....|.|: .....|......:.|....|...|
Worm   147 MILTQVPDLSRSPDTA-DFWRMIHQESIVSVVIAVMPLEVTLQQILPLLSGTYSTYGKMFVNNKK 210

  Fly  1659 VQQLSHCSEYQLKLSMHGADAVLDLSLLQLKQWTKGAPAQLLGVAENALETHRQRCKAANAPQSP 1723
            |:.....:||.|::...|....|..::..:..|.:....:::......:|      |.....::.
Worm   211 VESAVGMTEYCLEILPDGCSNSLLTTVYHMHNWRQKRGLEVVTDLVTTME------KVMKVNENS 269

  Fly  1724 LIMNCLTGSERS 1735
            ::|: :.|:.|:
Worm   270 VLMS-MNGTGRA 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	43/206 (21%)
		PTPc	1559..1745	CDD:238006	43/205 (21%)
Y116A8C.37	NP_503038.1	PTPc	87..283	CDD:214550	44/207 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900