DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and T27A3.5

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_491761.3	Gene:	T27A3.5 / 188965	WormBaseID:	WBGene00020841	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	371	Identity:	86/371 - (23%)
Similarity:	145/371 - (39%)	Gaps:	89/371 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1469 SVSEKQTKASATANGH-SSSFAFQSETFTD---------EKTTKYFQKEVESYEKLLENLHVKML 1523
            ||::|:   :|..|.. :|:...::|..|.         :|.:|..::..: |..:.|.:....:
Worm     3 SVNKKR---NARKNQEPTSNMTIETEDGTQADRPKKRPAKKRSKVVRRAAQ-YGDVNEPILRDFV 63

  Fly  1524 NGKTQLGAK---WQELQQKLDKEAAANKRSTTIAKLFPEKNRSLDCLPYDHARVKL---DKQTDD 1582
            ....|.|.|   .:.|..|::.: ..||..|. .:..|||||..|....|..||.|   :....|
Worm    64 KATIQTGVKQLSTEFLNLKMETQ-PCNKPKTG-HEGHPEKNRYKDVYCIDDTRVVLKWPEDSPSD 126

  Fly  1583 YINAAYMKNLSAGCPNFIVAQTPQPNTINDFWSMIWSEKSRTVVCL----HTPNELFDPYWPQAL 1643
            ||:|.::|  ..|...||..|.|...|::||:.:||.||:..||.|    ....:..:.|||:..
Worm   127 YIHANWVK--INGANKFICTQGPTEKTVDDFYRLIWQEKAPCVVMLCNIMECGKKKCEQYWPETA 189

  Fly  1644 D---------------QPTHYDDYTVTCLKVQQL-----SHCSEYQLKLSMHGADAVLDLSLLQL 1688
            |               :|....:..:..:|:..:     ||..|:                 .|.
Worm   190 DGQMILMDGKLTVKIAEPAKEVEQNILLMKITVIDDKGTSHNFEH-----------------WQW 237

  Fly  1689 KQW-TKGAPAQLLGVAENALETHRQRCKAANAPQSPLIMNCLTGSERS------ELVAIGVCAII 1746
            |.| .:|.|...:.|....:     |.|.|    ||::::|..|..|:      |:..:..||
Worm   238 KAWPDRGVPELPMAVFRLLI-----RLKTA----SPIVVHCSAGIGRTGSIVGLEIALVKFCA-- 291

  Fly  1747 ATQNKQPILLNTIDVWSRICAQRQNSLRDSAILEQSMQIVLCNAHN 1792
                .:.::|.  |:...|..||..|::..|......:::|..|.|
Worm   292 ----GEKVVLK--DIVKEIRNQRHGSVQTDAQYLFMHRVLLALAEN 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	63/263 (24%)
		PTPc	1559..1745	CDD:238006	54/219 (25%)
T27A3.5	NP_491761.3	PTPc	73..326	CDD:214550	68/290 (23%)
T27A3.5	NP_491761.3	PTPc	100..326	CDD:238006	62/261 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810