DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and F47B3.2

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_491277.1	Gene:	F47B3.2 / 185885	WormBaseID:	WBGene00018526	Length:	130	Species:	Caenorhabditis elegans

Alignment Length:	162	Identity:	35/162 - (21%)
Similarity:	55/162 - (33%)	Gaps:	70/162 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   581 AINEDDITGKVIAH----GGQEGLQALFATELGKHDKITELLDQNMVAQGNILQALTENYAKAAP 641
            |:|.|  |..|:.|    .|:.|      |.:|    |:.::|:  :.||          .....
Worm     9 AVNYD--TNPVVVHCSAGVGRSG------TIVG----ISLIMDK--MIQG----------INCKD 49

  Fly   642 VLKTLQDVKQKREHFYSSLAASY----------------DVYEDLL------AKSAKGLEFYKKL 684
            :.|.:::::.:| |:.....|.|                :.||.||      .|.||.|:.|...
Worm    50 MKKLVEEIRNQR-HYAIQTEAQYMYIHRVLLEYFLELHKETYEGLLLTKNYEEKYAKWLDDYNTY 113

  Fly   685 AGNVQKLLTRFRSARDVQSEERQQRMQSVKAA 716
            |                   |...|.|:.|||
Worm   114 A-------------------EANDRTQAAKAA 126

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747	29/146 (20%)
		ALIX_LYPXL_bnd	421..699	CDD:290660	29/143 (20%)
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528
		PTPc	1559..1745	CDD:238006
F47B3.2	NP_491277.1	PTPc_motif	<4..80	CDD:214649	19/95 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900