DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and F36H1.3

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_502058.3	Gene:	F36H1.3 / 185379	WormBaseID:	WBGene00009492	Length:	532	Species:	Caenorhabditis elegans

Alignment Length:	454	Identity:	101/454 - (22%)
Similarity:	164/454 - (36%)	Gaps:	126/454 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1437 SGPKCASLDNLSNCSDLSSLENFDWDSVSVTHSVSEKQT---KASATANG-HS----SSFAFQSE 1493
            ||.|        |||..|...|....|.....|..||::   |.||..|. |.    .:|||:.|
Worm    34 SGDK--------NCSKRSKKHNTKQKSKREKKSAREKKSLREKKSARENTMHDIFDRDTFAFRLE 90

  Fly  1494 TFTDEKTTKYFQKEVESYEKLLENLHVKMLNGKTQLGAKWQELQQKLDKEAAANKRSTTIAKLFP 1558
            .............:.|::|.....:        |.:|.           :..|.:...|:....|
Worm    91 HCVHPDALNRHSVQTEAFETFTTTV--------TSMGV-----------DGLAKEYLETLVPFLP 136

  Fly  1559 ---------------EKNRSLDCLPYDHARVKL-DKQTDDYINAAYMKNLSAGCPNFIVAQTPQP 1607
                           :|||..|....|..||.| |....||::|.|:|...   |.||:.|.|..
Worm   137 VGYFERSIFDKNTEFKKNRYKDVPCNDKTRVILKDGYPGDYVHANYVKGTK---PMFILTQGPLK 198

  Fly  1608 NTINDFWSMIWSEKSRTVVCLHTPNELF-------DPYWPQALDQPTHYDDYTVTCLKVQQLSHC 1665
            :|..|.|.|:..| ....:|:..  ||.       :||:|....|...:.:.||||  .:..:..
Worm   199 DTAMDIWRMVLQE-GVAAICMLC--ELIENGRPKCEPYFPDTEGQVLTFGEITVTC--TESTTPD 258

  Fly  1666 SEYQLKLSMHGADAVLD--------LSLLQLKQWTKGAPAQLLGVAENA-LETHRQRCKAANAPQ 1721
            :..|||:.     .|:|        |...::..|    |.:.:.::..| |.|.|...|.    .
Worm   259 NHTQLKML-----TVMDKKSGKSHKLYHYKIITW----PDKSIALSNLAILRTLRSLRKM----P 310

  Fly  1722 SPLIMNCLTGSERS---ELVAIGVCAIIATQNKQPI-LLNTIDVWSRICAQRQNSLR-DS----- 1776
            .|::::|..|..|:   ..:.:|...::..:..:|. |:..:    |.|  |.||:: |:
Worm   311 GPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAV----RHC--RLNSVQMDTQYLML 369

  Fly  1777 --AILEQSMQIVLCNAHNVLNKRGIMTSYQMKMAPQVTA-----------------KEQQENKD 1821
              |||:..:..........|:   .:.:|:..:|..|.|                 ||::::||
Worm   370 VEAILDLGVAFKYIEDPKSLD---AIETYKRNVADYVEAHPPPLEMFKAPPKVEIEKEKEKDKD 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	65/273 (24%)
		PTPc	1559..1745	CDD:238006	53/205 (26%)
F36H1.3	NP_502058.3	PTPc	122..375	CDD:214550	66/279 (24%)
F36H1.3	NP_502058.3	PTPc	152..375	CDD:238006	63/249 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900