DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and C15H7.3

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_499135.1	Gene:	C15H7.3 / 182639	WormBaseID:	WBGene00007610	Length:	398	Species:	Caenorhabditis elegans

Alignment Length:	343	Identity:	75/343 - (21%)
Similarity:	127/343 - (37%)	Gaps:	68/343 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1472 EKQTKASAT-------ANGHSS------SFAFQSETFT---DEKTTKYFQKEVESYEKLLENLHV 1520
            ||..|:..|       .||.:|      |.:.|||..|   |:|..|...|:.|..|:..|
Worm    37 EKSQKSRRTRKSRGPKGNGFTSRETIQPSSSGQSEGTTRMDDQKDEKKDDKKEEKKEERKE---- 97

  Fly  1521 KMLNGKTQLGAKWQELQQKLDKEAAANK--RSTTIAKLFPE-------------------KNRSL 1564
               ..|.::...|.|  ::..|...||.  .:|.:...|.:                   |.|:.
Worm    98 ---EKKEEVKEPWSE--EEPAKRMVANGFFTTTNVGGTFKQTDNFKTPMDSCPSFKNNMHKIRAP 157

  Fly  1565 DCLPYDHARVKLDKQTDDYINAAYMKNLSAGCPNF----IVAQTPQPNT---INDFWSMIWSEKS 1622
            ||...:...|||....:.:|.||.:.     .|:|    |:.|.|..::   |.|||.||..|..
Worm   158 DCPIPEEKLVKLTNGPESFICAAKIT-----VPDFNRTMILTQVPDLSSAPDIADFWRMIHQESI 217

  Fly  1623 RTVVCLHTPNEL-FDPYWPQALDQPTHYDDYTVTCLKVQQLSHCSEYQLKLSMHGADAVLDLSLL 1686
            .:||....|.|: .....|......:.|....|...||:.....:||.|::...|....|..::.
Worm   218 ASVVIAVMPLEVTLQQILPLLSGTYSTYGKMFVNNKKVESAVGMTEYCLEIFPDGCSNSLLTTVY 282

  Fly  1687 QLKQWTKGAPAQLLGVAENALETHRQRCKAANAPQSPLIMNCLTGSERSELVAIGVCAIIATQNK 1751
            .|..|.:....:::......:|      |......:.::|: :.|:.|:..:.....|::..|..
Worm   283 HLHNWRQKRGLEVVTDLVATME------KVMKVNDNTVLMS-MNGTGRAGTMLTLFTAMLQVQKG 340

  Fly  1752 QPILLNTIDVWSRICAQR 1769
            :.:  |..:..:.:.|:|
Worm   341 KEV--NAKETLASLRAER 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	48/239 (20%)
		PTPc	1559..1745	CDD:238006	43/212 (20%)
C15H7.3	NP_499135.1	PTPc	131..374	CDD:214550	49/240 (20%)
C15H7.3	NP_499135.1	PTPc	148..374	CDD:304379	48/223 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900