DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and B0507.2

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_001370343.1	Gene:	B0507.2 / 179255	WormBaseID:	WBGene00015219	Length:	427	Species:	Caenorhabditis elegans

Alignment Length:	402	Identity:	78/402 - (19%)
Similarity:	150/402 - (37%)	Gaps:	94/402 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 ETLRNQAMHTTKDGAPVMKRY--YCQLHA-----LQNRFPQLADRG----------IFTFKW-KD 95
            :.|.:|..:.:.|...|.|.:  |.:|.|     :|:...:|.::.          :..||| ..
Worm    41 DKLVSQFKNASNDLEEVTKEFNEYLRLFAGFLIEIQSSMVELENKDAGNKNSKLIPLIRFKWGNS 105

  Fly    96 LYHSAVHEVTDLRFERAAVLFNIAALHTQSGASVTRGD---VDGMKMACTHFQAAAWAYGELRER 157
            :...|..||:|..||..:::..:|...|:..||:...|   ....|......:.|...:..:::.
Worm   106 MLPQAATEVSDTWFEALSMIQCMAMWLTKHAASMAGKDEVRESDAKECLQCLRQAGGMFQYVKDE 170

  Fly   158 YANVNG-----GGDFMTPELLVFQQQVCFAQAQECILEKSLIDNRKPHIVAKVTAQIVVYYGAAL 217
            .:.::|     |.|| .|:::........|:|||.|:.:::.......:::.:         ||:
Worm   171 SSRLSGANEVEGSDF-DPKVMETYILTATAEAQEVIVARAIEMKHDDGLISSL---------AAV 225

  Fly   218 AALLTGGDDGPVAQVIDSSVYKLWKKYVRFKINYLTCILYLYQGQHSEEKRQMGERVTLYQASWD 282
            .|.:....|..:..:.|.| :..|::|::.|.::.....:.:.||     :|:.|         |
Worm   226 TASIFSKADQCLNNLPDES-FARWRRYLQLKHHFYLAYAFAFLGQ-----KQLSE---------D 275

  Fly   283 KLEEARKESK-GLPDQREINESLSFTA---------------------DVVEAKRKNAKNENEFI 325
            |..||.:..| |:.:.....|..:..|                     .::....:.|:.||.||
Worm   276 KCGEAVRACKQGIAEYGVAKEMAAMYATATGPGTRIKPEQHLFFRRIEPLLNRHLEKAERENGFI 340

  Fly   326 YHEAVPE---------------LSTIAAVQGANLVNGIGFQVSDEEHAGPDIFARLVPMKA---- 371
            ||:.||:               |.:......|...|...:...|...|....|:::...|:
Worm   341 YHQKVPDEIPQLDVEATYGLAKLDSFTYPPPAESWNTAVYSAFDLSKANMPDFSKIKKSKSKLDP 405

  Fly   372 -HEASSLYSEEK 382
             || ..:|..||
Worm   406 VHE-EKIYQTEK 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762	71/376 (19%)
		V_HD-PTP_like	368..702	CDD:185747	6/20 (30%)
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528
		PTPc	1559..1745	CDD:238006
B0507.2	NP_001370343.1	BRO1_Brox_like	4..366	CDD:185766	67/349 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2220
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810