DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and C55B7.3

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_001367695.1	Gene:	C55B7.3 / 172359	WormBaseID:	WBGene00016942	Length:	346	Species:	Caenorhabditis elegans

Alignment Length:	356	Identity:	81/356 - (22%)
Similarity:	139/356 - (39%)	Gaps:	73/356 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1476 KASATANGHSSSFAFQSETFTDEKTTKYFQKEVESY-EKLLENLHVKMLNGKTQLGAKWQELQQK 1539
            :|:.:||..:.|......|..:.|..|   |::..: ::.||    ||..|   |.|::..:::.
Worm    12 RATESANSSTKSSVLDEPTLVERKQQK---KQILKFVQRTLE----KMPQG---LRAEFVGMRRF 66

  Fly  1540 LDKEAAANKRSTTIAKLFPE-----KNRSLD--CLPYDHARVKLD-KQTDDYINAAYMKNLSAGC 1596
            .|.|.         .|.|.|     |||..|  ||  |:.||||: ....:||:|.|:.. ....
Worm    67 NDFEK---------MKAFKEAQEAGKNRYKDVGCL--DNNRVKLEGPWPHEYIHANYVAT-PTNP 119

  Fly  1597 PNFIVAQTPQPNTINDFWSMIWSEKSRTVVCL-----HTPNELFDPYWPQALDQPTHYDD----Y 1652
            ..||..|.|...|..|||.|.:.:|...:..|     ....:.|: |:|........:::    .
Worm   120 KRFICTQAPLEKTCADFWYMCYQDKVEYIFMLCNLLEKGARKCFE-YFPSKKGDVMDFEEGGQKI 183

  Fly  1653 TVTCLKVQQLSHCSEYQLKLSMHGADAVLD--------LSLLQLKQW-TKGAPAQLLGVAENALE 1708
            :|.|  ...:::......|.::...:.|::        .:......| .:|.||..:.|.| .||
Worm   184 SVKC--ESSVTYSFRSDAKANVTATEIVIEGPGEKTRKTTHYHWNDWPDRGVPAADMAVLE-LLE 245

  Fly  1709 THRQRCKAANAPQSPLIMNCLTGSERSELVAIGVCAIIATQNKQPILLNTID----VWSRICAQR 1769
            .       |...:.|::::|..|..|:     |...::.....|.:....||    :..:|..||
Worm   246 N-------ARPSKGPIVVHCSAGIGRT-----GSVVMLEYIMDQLLAGQIIDDGEKILVKIREQR 298

  Fly  1770 QNSLRDSAILEQSMQIVLCNAHNVLNKRGIM 1800
            .||::..|......|::|    |...|:.:|
Worm   299 NNSIQTDAQYLFVHQVIL----NYFRKKKLM 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	58/259 (22%)
		PTPc	1559..1745	CDD:238006	48/211 (23%)
C55B7.3	NP_001367695.1	Y_phosphatase	83..317	CDD:395053	58/256 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900