DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mop and ptprr

DIOPT Version :9

Sequence 1:	NP_648722.2	Gene:	mop / 39610	FlyBaseID:	FBgn0036448	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	XP_021330980.1	Gene:	ptprr / 100526652	ZFINID:	ZDB-GENE-101029-2	Length:	639	Species:	Danio rerio

Alignment Length:	448	Identity:	110/448 - (24%)
Similarity:	160/448 - (35%)	Gaps:	99/448 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1369 IDCSVAVPPPMLPQPVLQPQVVATPTPP---------ASQVSVPVKVESVAEHAAPA-TAEIPVA 1423
            :|..:..|.|......|.|..|....||         ||:.|.|......:...||: ...|...
Zfish   211 LDQQLKDPSPPSRDVHLAPVPVHGAQPPLTLKNSMVQASRTSKPSATYFPSSTNAPSCNISIHQT 275

  Fly  1424 ATEGTAQTPVTIPSGPKCASLDNLSNCSDLSSLENFDWDSVSVTHS-VSEKQTKASATANGHSSS 1487
            .:.||...| ..||||..|.|.                .|||.||| ...|.........|.:.|
Zfish   276 PSSGTTSEP-QCPSGPPAAELK----------------PSVSCTHSPFRMKPVAGLQERRGSNVS 323

  Fly  1488 FAFQSETFTD------------EKTTKYFQKEVESYEKLLENLHVKMLNGKTQ----LGAKWQEL 1536
            ......:...            |:.|   |:.::|..::|..   |.|...||    |.|::.|:
Zfish   324 LVLDMSSLGSVEPLNCGVVTPRERAT---QEYLQSASRVLSR---KQLRDVTQNTHVLHAEFAEI 382

  Fly  1537 ------QQKLDKEAAANKRSTTIAKLFPEKNRSLDCLPYDHARVKL-DKQTDD----YINAAYMK 1590
                  |::||   ..|..|         |||....||..|:||.| .|.::|    ||||.|::
Zfish   383 PMNFVDQKELD---VPNHGS---------KNRYKTILPNPHSRVILKTKNSNDPLSSYINANYIR 435

  Fly  1591 NLSAGCPNFIVAQTPQPNTINDFWSMIWSEKSRTVVC---LHTPNELFDPYWPQALDQPTHYDDY 1652
            ........||..|.|..||:||||.|:|.|....:|.   |...||....|||:      ....|
Zfish   436 GYLGVERAFIATQGPMINTVNDFWQMVWQEDCPVIVMITKLKEKNEKCVLYWPE------KRGIY 494

  Fly  1653 TVTCLKVQQLSHCSEYQLK-LSMHGADAVLDLSLLQLKQW----TKGAPAQLLGVAENALETHRQ 1712
            ....:.|..:..|..|.:: |::........:.......|    |..:...||.:. |.:|..|:
Zfish   495 GKVEVSVNNVKECDHYIIRTLNLKNGGQSRKVQHYWYTSWPDHKTPESAGPLLQLV-NDVEEDRK 558

  Fly  1713 RCKAANAPQSPLIMNCLTGSERSELVAIGVCAIIATQN-KQPILLNTIDVWSRICAQR 1769
            ...::    .|::::|..|..|:.      |.:..|.. :|..|...:||...:|..|
Zfish   559 GWTSS----GPVVVHCSAGIGRTG------CFMATTIGCRQLGLEGLVDVLGIVCQLR 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762
		V_HD-PTP_like	368..702	CDD:185747
		ALIX_LYPXL_bnd	421..699	CDD:290660
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528	60/226 (27%)
		PTPc	1559..1745	CDD:238006	53/198 (27%)
ptprr	XP_021330980.1	PTPc	400..626	CDD:238006	60/224 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000