Protein Alignment Mgat4b and MGAT4D

DIOPT Version :10

• Sequence 1: NP_648721.1
• Gene: Mgat4b / 39609
• FlyBaseID: FBgn0036447
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001264282.1
• Gene: MGAT4D / 152586
• HGNCID: 43619
• Length: 374
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 96/318 - (30%)
• Similarity: 157/318 - (49%)
• Gaps: 33/318 - (10%)

  Fly    31 DITKIEPVEPRVVKNKTKVPRMYAKTINHDGNWETIVTN--------PELK------PRYRVGGG 81
            :|||.|.:...:|..|       |..:|.:   ||:...        |.|:      |...:|.|
Human    73 EITKREILSGNLVAQK-------ADILNKN---ETVSNTFEDLKFFFPHLRKEGRIYPDVIIGKG 127

  Fly    82 RTGVQFVIGVPTVLRPKKNYVLQTVDCLIRRMTPEQRDNCLIVIFVGETKLQFAKFIVRELRVNH 146
            :|||.|.:|:.||.|...:|:.||:..::.|||..|..:.::::.|.::...:...:|:.:....
Human   128 KTGVSFALGISTVNRGNYSYLKQTLTSVVSRMTLSQEKDSVVIVLVADSNEDYLHSVVKMITKKF 192

  Fly   147 STHMQAGLIDVIAPPLNYYPNFSRLHITLNDDPQRVQWRTKQNLDYIYLMSYAKSRGLYYLQLED 211
            ...:::|.::||:.|...|.:............:...||.||.||:..|:.||:.:..|||||||
Human   193 KRQVRSGSLEVISIPAFLYSSMLNAKHLAEASQKLASWRIKQVLDFCILLLYAQPKAKYYLQLED 257

  Fly   212 DVMANVGFMDYIQKFAVLHGSFRIAQQIDWIVMSFSELGFIGKLFRTSVLSSFVAYLKLFYNDQP 276
            |::|...:...|..|.   |:.   ...:|..:.||.|||||||||:..|:.||.:..:||.::|
Human   258 DIIAKEMYFTKITDFV---GNI---SSNNWFFIEFSMLGFIGKLFRSEDLTHFVRFFLMFYKEKP 316

  Fly   277 IDWLLQSFVTLQSCRWDSVSD-PECQRDFESRLLRSSQSQFQHMGAQSSLADKQQYQK 333
            |||||.....::.|  |:..| ..|.:..:...::...|.|||:|..||...|:||:|
Human   317 IDWLLNDIFQVKVC--DAGEDLRNCMKRKKQIRIQYKPSLFQHVGIHSSFPRKEQYEK 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mgat4b	NP_648721.1	Glyco_transf_54	30..337	CDD:461384	96/318 (30%)
		putative TM2 helix	243..263	CDD:409189	12/19 (63%)
MGAT4D	NP_001264282.1	Glyco_transf_54	96..372	CDD:461384	87/283 (31%)