Protein Alignment Mgat4b and MGAT4B

DIOPT Version :10

• Sequence 1: NP_648721.1
• Gene: Mgat4b / 39609
• FlyBaseID: FBgn0036447
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_463459.1
• Gene: MGAT4B / 11282
• HGNCID: 7048
• Length: 563
• Species: Homo sapiens
• Alignment Length: 407
• Identity: 133/407 - (32%)
• Similarity: 214/407 - (52%)
• Gaps: 65/407 - (15%)

  Fly    60 DGN--WETIVTNPELK------------------------------PRYRVGGGRTGVQFVIGVP 92
            |||  |..:..:|.||                              |..|||.|||||..|:|:|
Human   100 DGNRTWGRLTEDPRLKPWNGSHRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQGRTGVSVVMGIP 164

  Fly    93 TVLRPKKNYVLQTVDCLIRRMTPEQRDNCLIVIFVGETKLQFAKFIVRELRVNHSTHMQAGLIDV 157
            :|.|...:|:..|:..||..::|:::::.:||:.:.||..|:...:...::....|.:.:||::|
Human   165 SVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDSQYTSAVTENIKALFPTEIHSGLLEV 229

  Fly   158 IAPPLNYYPNFSRLHITLNDDPQRVQWRTKQNLDYIYLMSYAKSRGLYYLQLEDDVMANVGFMDY 222
            |:|..::||:||||..:..|..:||:|||||||||.:||.||:|:|:||:|||||::|...::..
Human   230 ISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLST 294

  Fly   223 IQKFAVLHGSFRIAQQIDWIVMSFSELGFIGKLFRTSVLSSFVAYLKLFYNDQPIDWLLQSFVTL 287
            ::.||:...|      .||:::.||:||||||:|::..||..|.::.:||.|:||||||...:
Human   295 MKNFALQQPS------EDWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRDKPIDWLLDHIL-- 351

  Fly   288 QSCRWDSVSDPE-----CQRDFESRLLRSSQSQFQHMGAQSSLADKQQYQKDAFFNHNFARQRLR 347
                |..|.:||     |.|...:..:|...|.|||:|..||||.|.|..||    .:|.:|.||
Human   352 ----WVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKD----KDFGKQALR 408

  Fly   348 --HLRQPLNL---IATHRN-SLLKHNLDLVEGETFIWIYMPRMPKMMKYLITNQFKQTQLHIR-- 404
              |:..|..:   :.|::: :|.|..|    .|.|.|.:.|.....:::......:..:...|
Human   409 KEHVNPPAEVSTSLKTYQHFTLEKAYL----REDFFWAFTPAAGDFIRFRFFQPLRLERFFFRSG 469

  Fly   405 NAKDTAHNLAEFNIELV 421
            |.:.....|...::|::
Human   470 NIEHPEDKLFNTSVEVL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mgat4b	NP_648721.1	Glyco_transf_54	30..337	CDD:461384	115/313 (37%)
		putative TM2 helix	243..263	CDD:409189	10/19 (53%)
MGAT4B	NP_463459.1	Glyco_transf_54	125..402	CDD:461384	108/292 (37%)
		putative TM2 helix	309..329	CDD:409189	10/19 (53%)