DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9384 and Mgat4b

DIOPT Version :9

Sequence 1:	NP_001261847.1	Gene:	CG9384 / 39608	FlyBaseID:	FBgn0036446	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_006246312.1	Gene:	Mgat4b / 303100	RGDID:	1562836	Length:	576	Species:	Rattus norvegicus

Alignment Length:	512	Identity:	215/512 - (41%)
Similarity:	303/512 - (59%)	Gaps:	63/512 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 RQLLRNASHISKGGSANGSMARSQNIR-----------LPNAYHFLPHLLDDAGSLRPAYLQSKG 157
            ||.||:    .:|....|.:.....::           ||..:|.|||||....||:||....:|
  Rat    78 RQALRD----GEGNRTWGRLTEDPRLKPWNVSHRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQG 138

  Fly   158 RSDVSIVLGVPTVRREKQSYLLGTLHNLIENMNDEEQNETLIIVYIGETDMESVQLIARQIESSF 222
            |:.||:|:|:|:||||..|||..|||:||..::.:|:.:::|:|.|.|||.:....:...|::.|
  Rat   139 RTGVSVVMGIPSVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDTQYTSAVTENIKALF 203

  Fly   223 DQHVESGLIDIIAPAPSYYPNFERLRITLNDPLERVKWRSKQNLDFAYLMAYAHSKGTFYVQLED 287
            ...:.|||:::|:|:|.:||:|.|||.:..||.|||:||:|||||:.:||.||.|||.:||||||
  Rat   204 PTEIHSGLLEVISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLED 268

  Fly   288 DILTKRQFITTMKKFALIKSALTKPDQP--EWFVLDFCQLGFIGKMFKSAELPYLITYFQMFYND 350
            ||:.|..:::|||.|||        .||  :|.:|:|.|||||||||||.:|..::.:..|||.|
  Rat   269 DIVAKPNYLSTMKNFAL--------QQPSEDWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRD 325

  Fly   351 KPVDWLLTYFIESKVCRTDKDQKHCNAEKAKYWQHFRKSLFQHIGTSSSLKGKVQKLKDKQFGSK 415
            ||:||||.:.:..|||..:||.|||:.:||.....|:.|||||:||.|||.||:||||||.|| |
  Rat   326 KPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFG-K 389

  Fly   416 VPQYYAHTHNPPALVKSNIAPYKNYLLQRAYRGESYFWGLLPQPGDLVQIIFERPTQLR------ 474
            ......|. ||||.|.:::..|:::.|::||..|.:||...|..||.::..|.:|.:|.
  Rat   390 HALRKEHV-NPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLERPGMAF 453

  Fly   475 ----------------------HYLFRSGNSEHPSDRFYNTTVELLPAD-------TLSENSSVW 510
                                  .:.|||||.|||.|:.:||:||:||.|       .|.|..|..
  Rat   454 SLLGLDRGSWAVLRLTGPLGVCRFFFRSGNIEHPEDKLFNTSVEVLPFDNPQSEKEALQEGRSAT 518

  Fly   511 SSYNTTTDGYLVVGSFDSMGVAEGLLDAKIGAIKELRLHVHSDSENWALLSEIELQE 567
            ..|..:.||||.:||| ..|||||.:|...|.::.|||.:.:||..|.:||||.|::
  Rat   519 LRYPRSPDGYLQIGSF-YKGVAEGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKK 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9384	NP_001261847.1	Glyco_transf_54	129..412	CDD:282514	142/295 (48%)
Mgat4b	XP_006246312.1	Glyco_transf_54	110..387	CDD:282514	142/284 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342006
Domainoid	1	1.000	307	1.000	Domainoid score	I1303
eggNOG	1	0.900	-	-		E1_28HC5
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	421	1.000	Inparanoid score	I1729
OMA	1	1.010	-	-		QHG48935
OrthoDB	1	1.010	-	-		D268757at33208
OrthoFinder	1	1.000	-	-		FOG0002296
OrthoInspector	1	1.000	-	-		otm45021
orthoMCL	1	0.900	-	-		OOG6_104024
Panther	1	1.100	-	-	LDO	PTHR12062
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1731
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770