Protein Alignment Mgat4a and Mgat4b

DIOPT Version :10

• Sequence 1: NP_648720.3
• Gene: Mgat4a / 39608
• FlyBaseID: FBgn0036446
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_006246312.1
• Gene: Mgat4b / 303100
• RGDID: 1562836
• Length: 576
• Species: Rattus norvegicus
• Alignment Length: 513
• Identity: 214/513 - (41%)
• Similarity: 302/513 - (58%)
• Gaps: 65/513 - (12%)

  Fly   104 RQLLRNASHISKGGSANGSMARSQNIR-----------LPNAYHFLPHLLDDAGSLRPAYLQSKG 157
            ||.||:    .:|....|.:.....::           ||..:|.|||||....||:||....:|
  Rat    78 RQALRD----GEGNRTWGRLTEDPRLKPWNVSHRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQG 138

  Fly   158 RSDVSIVLGVPTVRREKQSYLLGTLHNLIENMNDEEQNETLIIVYIGETDMESVQLIARQIESSF 222
            |:.||:|:|:|:||||..|||..|||:||..::.:|:.:::|:|.|.|||.:....:...|::.|
  Rat   139 RTGVSVVMGIPSVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDTQYTSAVTENIKALF 203

  Fly   223 DQHVESGLIDIIAPAPSYYPNFERLRITLNDPLERVKWRSKQNLDFAYLMAYAHSKGTFYVQLED 287
            ...:.|||:::|:|:|.:||:|.|||.:..||.|||:||:|||||:.:||.||.|||.:||||||
  Rat   204 PTEIHSGLLEVISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLED 268

  Fly   288 DILTKRQFITTMKKFALIKSALTKPDQP--EWFVLDFCQLGFIGKMFKSAELPYLITYFQMFYND 350
            ||:.|..:::|||.|||        .||  :|.:|:|.|||||||||||.:|..::.:..|||.|
  Rat   269 DIVAKPNYLSTMKNFAL--------QQPSEDWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRD 325

  Fly   351 KPVDWLLTYFIESKVCRTDKDQKHCNAEKAKYWQHFRKSLFQHIGTSSSLKGKVQKLKDKQFGSK 415
            ||:||||.:.:..|||..:||.|||:.:||.....|:.|||||:||.|||.||:||||||.||..
  Rat   326 KPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKH 390

  Fly   416 VPQYYAHTH-NPPALVKSNIAPYKNYLLQRAYRGESYFWGLLPQPGDLVQIIFERPTQLR----- 474
            .   ....| ||||.|.:::..|:::.|::||..|.:||...|..||.::..|.:|.:|.
  Rat   391 A---LRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLERPGMA 452

  Fly   475 -----------------------HYLFRSGNSEHPSDRFYNTTVELLPAD-------TLSENSSV 509
                                   .:.|||||.|||.|:.:||:||:||.|       .|.|..|.
  Rat   453 FSLLGLDRGSWAVLRLTGPLGVCRFFFRSGNIEHPEDKLFNTSVEVLPFDNPQSEKEALQEGRSA 517

  Fly   510 WSSYNTTTDGYLVVGSFDSMGVAEGLLDAKIGAIKELRLHVHSDSENWALLSEIELQE 567
            ...|..:.||||.:||| ..|||||.:|...|.::.|||.:.:||..|.:||||.|::
  Rat   518 TLRYPRSPDGYLQIGSF-YKGVAEGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKK 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mgat4a	NP_648720.3	Glyco_transf_54	129..412	CDD:461384	142/295 (48%)
Mgat4b	XP_006246312.1	Glyco_transf_54	110..387	CDD:461384	142/284 (50%)
		putative TM2 helix	294..314	CDD:409189	14/19 (74%)