Protein Alignment Mgat4a and Mgat4a

DIOPT Version :10

• Sequence 1: NP_648720.3
• Gene: Mgat4a / 39608
• FlyBaseID: FBgn0036446
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_036021327.1
• Gene: Mgat4a / 269181
• MGIID: 2662992
• Length: 572
• Species: Mus musculus
• Alignment Length: 608
• Identity: 223/608 - (36%)
• Similarity: 331/608 - (54%)
• Gaps: 91/608 - (14%)

  Fly     9 CMLIVTA----------------LVLAPCIVIL---------MVMGPELS--TEQSLTQRLAECH 46
            |:|::.|                .||..|.|.|         :|:.|.|.  :..|..|..:.|.
Mouse     4 CLLVLEAGREEGAGLVPAHYPLPDVLRVCCVYLKEEQWTVPSLVLAPALQSVSSSSFRQGFSVCC 68

  Fly    47 MRLQYLESMYRARQEDVAL----LSQYLGQLQIVNVTGASAPPPPPPLPVVNLLDGLSPEARQLL 107
            .:|...:..:.|.:|.:.:    :||...:|..:                           .|..
Mouse    69 EKLIAYQREFLALKERLRVAEHRISQRSSELNTI---------------------------VQQF 106

  Fly   108 RNASHISKGGSANGS-----------------MARSQNIRLPNAYHFLPHLLDDAGSLRPAYLQS 155
            |.|     |...|||                 :...:::|:|:.|:.|||||.:..||:||....
Mouse   107 RRA-----GAETNGSKTALSTISDNTIKLLKELTSKKSLRVPSIYYHLPHLLQNERSLQPAVQIG 166

  Fly   156 KGRSDVSIVLGVPTVRREKQSYLLGTLHNLIENMNDEEQNETLIIVYIGETDMESVQLIARQIES 220
            .||:.||||:|:|||:||.:|||:.|||:||:|:..||:.:.:|:|:|||||::.|..:...:|.
Mouse   167 SGRTGVSIVMGIPTVKREVKSYLVETLHSLIDNLYPEEKLDCVIVVFIGETDLDYVHSVVANLEK 231

  Fly   221 SFDQHVESGLIDIIAPAPSYYPNFERLRITLNDPLERVKWRSKQNLDFAYLMAYAHSKGTFYVQL 285
            .|.:.:.|||::||:|..||||:...|:.|..|..|||:||:|||||:.:||.||..||.:|:||
Mouse   232 EFSREISSGLLEIISPPESYYPDLTNLKETFGDSKERVRWRTKQNLDYCFLMMYAQEKGIYYIQL 296

  Fly   286 EDDILTKRQFITTMKKFALIKSALTKPDQPEWFVLDFCQLGFIGKMFKSAELPYLITYFQMFYND 350
            ||||:.|:.:..|:|.|||..|:      .||.:|:|.|||||||||::.:|..::.:..|||.:
Mouse   297 EDDIIVKQNYFNTIKNFALQLSS------EEWMILEFSQLGFIGKMFQAPDLALVVEFILMFYKE 355

  Fly   351 KPVDWLLTYFIESKVCRTDKDQKHCNAEKAKYWQHFRKSLFQHIGTSSSLKGKVQKLKDKQFGSK 415
            ||:||||.:.:..|||..:||.|||:.:||.....||.|||||:|..|||.||:|||.||.:
Mouse   356 KPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFRPSLFQHVGLHSSLSGKIQKLTDKDY--- 417

  Fly   416 VPQYYAHTH-NPPALVKSNIAPYKNYLLQRAYRGESYFWGLLPQPGDLVQIIFERPTQLRHYLFR 479
            :.......| ||||.|.:::..|:.:.|::.|.||.:||.:.|..||.:...|::|..:..|||.
Mouse   418 MKPLLLKVHVNPPAEVSTSLKVYQGHTLEKTYMGEDFFWAITPTAGDYILFKFDKPVNVESYLFH 482

  Fly   480 SGNSEHPSDRFYNTTVELLPADTLSENSSVWSSYNTTTDGYLVVGSFDSMGVAEGLLDAKIGAIK 544
            |||.|||.|...||||::||..:.|...|..:......|||..:|.|: .|||||::|..:..|.
Mouse   483 SGNQEHPGDILLNTTVDVLPLKSDSLEISKETKDKRLEDGYFRIGKFE-YGVAEGIVDPGLNPIS 546

  Fly   545 ELRLHVHSDSENWALLSEIELQE 567
            ..||.|..:|..||:|:||.:::
Mouse   547 AFRLSVIQNSAVWAILNEIHIKK 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mgat4a	NP_648720.3	Glyco_transf_54	129..412	CDD:461384	139/282 (49%)
Mgat4a	XP_036021327.1	Glyco_transf_54	140..417	CDD:461384	131/276 (47%)
		putative TM2 helix	324..339	CDD:409189	5/14 (36%)