DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13473 and Y49E10.4

DIOPT Version :9

Sequence 1:	NP_648717.1	Gene:	CG13473 / 39603	FlyBaseID:	FBgn0036442	Length:	139	Species:	Drosophila melanogaster
Sequence 2:	NP_499613.1	Gene:	Y49E10.4 / 176664	WormBaseID:	WBGene00013030	Length:	436	Species:	Caenorhabditis elegans

Alignment Length:	185	Identity:	45/185 - (24%)
Similarity:	67/185 - (36%)	Gaps:	65/185 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KKVIIVDSKSYFDKLIDDAGTNKYVLVEFFATWCGPCAMIGPRLEQLASDYFGRMLVLKIDVDEN 70
            |.|::.||.  ||||:  ..:.:..:|||||.|||.|..:.|..::.|.:..||:....:|...:
Worm   155 KVVVLTDSN--FDKLV--LNSKEPWMVEFFAPWCGHCQKLEPEWKKAAEEMGGRVKFGALDATAH 215

  Fly    71 EDLAVQYEVNSMPTFLII----------------KNRVTLIQF--------------VGGNVERV 105
            |.:|.::.:...||....                :....||.:              |.|..:.|
Worm   216 ESIAQKFGIRGFPTIKFFAPGTSSASDAEDYQGGRTSTDLISYAESKYDDFGAAPEVVEGTGKAV 280

  Fly   106 VSTVEK--------FVGKVED--SKEHKSK---------------------EGGA 129
            |.||.|        |:..:.|  ||..|.|                     ||||
Worm   281 VETVCKDKQLCIFTFLPSIFDCQSKCRKQKIDMLNELATIFKKRSFGWVWMEGGA 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13473	NP_648717.1	Thioredoxin	8..111	CDD:278513	33/132 (25%)
Y49E10.4	NP_499613.1	PDI_a_P5	26..127	CDD:239299
		PDI_a_P5	156..259	CDD:239299	27/106 (25%)
		P5_C	269..405	CDD:239281	17/67 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910