Protein Alignment CG17177 and PCCB

DIOPT Version :10

• Sequence 1: NP_648715.1
• Gene: CG17177 / 39601
• FlyBaseID: FBgn0036440
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: NP_001171485.1
• Gene: PCCB / 5096
• HGNCID: 8654
• Length: 559
• Species: Homo sapiens
• Alignment Length: 526
• Identity: 96/526 - (18%)
• Similarity: 176/526 - (33%)
• Gaps: 178/526 - (33%)

  Fly   682 DKNETKGE--FTGSTNED-----VFIQQCECHAQVSIASLLLVISAITVATNTHDYGNIYNQIRA 739
            |||:..|:  .||....:     ||.||....||    .|.|||||:..|.:...:|...:...|
Human    98 DKNKFPGDSVVTGRGRINGRLVYVFSQQIIGWAQ----WLPLVISALWEAEDFTVFGGSLSGAHA 158

  Fly   740 PPVKERCDDYNDISKWIAEQVKLSAQLRKFQRDQNAILSYFYKTPTSMTCRFYEEITLN-----R 799
                      ..|.|.:.:.:.:.|.:                            |.||     |
Human   159 ----------QKICKIMDQAITVGAPV----------------------------IGLNDSGGAR 185

  Fly   800 IVEKVNRINEISESQVEKLKISGDLEKDVENVLPQIKKFVSKGIKSCC---------ENFTKLIE 855
            |.|.|..:...::..:..:..||        |:|||...:.    .|.         .:||.::
Human   186 IQEGVESLAGYADIFLRNVTASG--------VIPQISLIMG----PCAGGAVYSPALTDFTFMV- 237

  Fly   856 HYKKDLHL------KIKNLPNKLNETESEKLN--ESHSIQKNLGY--IEKQVE---EIRPLFQKL 907
              |...:|      .:|::.|:  :...|:|.  ::|:....:.:  .|..|:   .:|..|..|
Human   238 --KDTSYLFITGPDVVKSVTNE--DVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFFNYL 298

  Fly   908 QKYFRDSQANSKCCDGLKESFQSLENKLSIIKSNGYN-----QSLKIENQLKELKDKIQENV--- 964
            ....:|.....:|.|........|:..:.:..:..||     .|:..|.:..|:.....:|:
Human   299 PLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDEREFFEIMPNYAKNIIVG 363

  Fly   965 -------------EKTK------DIKTTL-SHRFENIKNILGICNQSYIHQNVPMDTTIFLD--- 1006
                         .:.|      ||.::: ..||      :..|:..    |:|:.|  |:|
Human   364 FARMNGRTVGIVGNQPKVASGCLDINSSVKGARF------VRFCDAF----NIPLIT--FVDVPG 416

  Fly  1007 ------------LEKNAETLEKLAETLFKKLGVL--DIHKPSINLNVTLNTCQENNEMLTNIQ-S 1056
                        :...|:.|...||....|:.|:  ..:..:.::..:.:.|.:.|......: :
Human   417 FLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGDTNYAWPTAEIA 481

  Fly  1057 KMGYLLKQNSKDCFEGSPTDSKNSKSLIIKTCSSNEKLQNSIAELEKEIGILRKELNKFPKCCKK 1121
            .||                 :|.:..:|.|   .:|.::.:.||      .:.|..|.||...:.
Human   482 VMG-----------------AKGAVEIIFK---GHENVEAAQAE------YIEKFANPFPAAVRG 520

  Fly  1122 -IDDLI 1126
             :||:|
Human   521 FVDDII 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17177	NP_648715.1	PRK12704	111..>264	CDD:237177
		SMC_prok_B	125..>424	CDD:274008
		CwlO1	399..>580	CDD:443091
		SMC_N	1092..>1297	CDD:481474	10/36 (28%)
PCCB	NP_001171485.1	MmdA	37..557	CDD:443827	96/526 (18%)