Protein Alignment LGALS4 and CG5335

DIOPT Version :10

• Sequence 1: NP_006140.1
• Gene: LGALS4 / 3960
• HGNCID: 6565
• Length: 323
• Species: Homo sapiens
• Sequence 2: NP_611349.2
• Gene: CG5335 / 37140
• FlyBaseID: FBgn0034365
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 283
• Identity: 74/283 - (26%)
• Similarity: 111/283 - (39%)
• Gaps: 54/283 - (19%)

Human    35 IQGVASEHMKRFFVNFVVGQ---DPGSDVAFHFNPRFDGWDKVVFNTLQGGKWGSEE------RK 90
            |.|.|     ||.:|....:   ||.:|:...|:..|.. |.:|.|:...|.||.||      ..
  Fly    26 IDGAA-----RFHINLCTAKSTVDPNADIGLRFSCYFRN-DVIVRNSRINGAWGEEESHVMDPNT 84

Human    91 RSMPFKKGAAFELVFIVLAE-HYKVVVNGNPFYEYGHRLPLQMVTHLQVDGDLQLQSINFIGGQP 154
            ...|...|..| ||:|:..| .:.:.:|...|..:.:|:||..:..|::..  |:|.|..:..:.
  Fly    85 LPNPIVSGEFF-LVYILCCEDSFAISINSREFCRFRYRMPLGTIRALEIRD--QIQVIKQVDHRT 146

Human   155 LRPQGPPMMPPYPGPGHCHQQLNSLPTMEGPPTFNPPVPYFGRLQGG----LTARRTIIIKGYVP 215
            :.|.      |:|.. |......:. :.:.|..|:|          |    ||||.....||
  Fly   147 VFPN------PWPAV-HASDYFKAF-SNDQPILFSP----------GHVIVLTARCFENKKG--- 190

Human   216 PTGKSFAINFKVGSSGDIALHINPRMGNGTVVRNSL-LNGSWGSEEKKITHN--PFGPGQFFDLS 277
                .|.|.|....:....||.:.|.....|||||: .|..:||||:   |.  ||...|.|.|:
  Fly   191 ----QFIIKFMDSDTKREELHFSVRFDEKAVVRNSMNKNFEFGSEER---HGGFPFVFNQQFKLA 248

Human   278 IRCGLDRFKVYANGQHLFDFAHR 300
            :...........:|.:.|.:..|
  Fly   249 LAFTEREVLTAVDGYNFFSYTWR 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LGALS4	NP_006140.1	GLECT	18..147	CDD:238025	34/121 (28%)
		Gal-bind_lectin	199..322	CDD:214904	32/109 (29%)
CG5335	NP_611349.2	Gal-bind_lectin	12..140	CDD:459768	34/122 (28%)
		GLECT	172..297	CDD:238025	34/120 (28%)