Protein Alignment LGALS4 and galectin

DIOPT Version :10

• Sequence 1: NP_006140.1
• Gene: LGALS4 / 3960
• HGNCID: 6565
• Length: 323
• Species: Homo sapiens
• Sequence 2: NP_608487.1
• Gene: galectin / 33162
• FlyBaseID: FBgn0031213
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 353
• Identity: 109/353 - (30%)
• Similarity: 155/353 - (43%)
• Gaps: 54/353 - (15%)

Human    13 YNPTLP-YYQPIPGGLNVGMSVYIQGVASEHMKRFFVNFVVGQDPGSDVAFHFNPRFDGWDKVVF 76
            |...:| |:....|.|:.|:|..:.|..|.:.:||.:|.|...| ..|||.|.|||.. .:.:|.
  Fly   131 YADAVPKYFNDQIGKLSEGISFTVTGNLSVNCERFSINLVYNND-SRDVALHINPRLP-QNYIVR 193

Human    77 NTLQGGKWGSEERKRSMPF--KKGAAFELVFIVLAEHYKVVVNGNPFYEYGHRLPLQMVTHLQVD 139
            ||.....||:||...::||  .:|..|.:..:|....|.:.|||..|..|.||:|.:.|..|:|.
  Fly   194 NTKVQDIWGNEEVSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRIPYRDVRILEVK 258

Human   140 GDLQLQSINFIGGQPLRPQGPPMMPPYPGPG---HCHQQLNSLPT--------------MEGPPT 187
            ||:.    |....:.|..:.|..:|......   |....:|.:..              :..|.|
  Fly   259 GDVS----NVEMKRTLVLKYPERLPQSEANNIELHIDDGINEIDASVEETVKIPHEWCIISAPNT 319

Human   188 --------------FNPPVPYFGRL-QGGLTARRTIIIKGYVPPTGKSFAINFKVGSS----GDI 233
                          ....:||:|.| ...|...|.:.|:|.|.....||.||.:.|..    ..|
  Fly   320 QSDSSPKRNNSSNDLGLTLPYYGALPPNSLVDGRCLKIEGRVRLLPHSFYINLQQGQDIWPHPVI 384

Human   234 ALHINPR--------MGNGTVVRNSLLNGSWGSEEKKITHNPFGPGQFFDLSIRCGLDRFKVYAN 290
            |.|:|||        :|...|.||:.|||:|..||:......|.||:.|.|:|.|....|:||.|
  Fly   385 AFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQEERSEFDTNFRPGRSFCLAIVCTKTSFEVYVN 449

Human   291 GQHLFDFAHRLSAFQRVDTLEIQGDVTL 318
            .|.:.||.:::|. :.|||:.|||||.|
  Fly   450 RQFMTDFKYKVSP-EVVDTVYIQGDVKL 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LGALS4	NP_006140.1	GLECT	18..147	CDD:238025	46/131 (35%)
		Gal-bind_lectin	199..322	CDD:214904	50/132 (38%)
galectin	NP_608487.1	GLECT	143..262	CDD:238025	44/120 (37%)
		Gal-bind_lectin	346..479	CDD:459768	50/132 (38%)