Protein Alignment ARHGDIA and RhoGDI

DIOPT Version :9

• Sequence 1: NP_001288171.1
• Gene: ARHGDIA / 396
• HGNCID: 678
• Length: 337
• Species: Homo sapiens
• Sequence 2: NP_001262080.1
• Gene: RhoGDI / 40179
• FlyBaseID: FBgn0036921
• Length: 201
• Species: Drosophila melanogaster
• Alignment Length: 137
• Identity: 67/137 - (48%)
• Similarity: 91/137 - (66%)
• Gaps: 5/137 - (3%)

Human    18 NEEDEHSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGRV---AVSADPNVP-NVVVTGLTLV 78
            :::|.|..||:.|.:|:|:||...|::|||||:|||||||..   .:..:||.| .|:|..|.||
  Fly    13 HDDDVHDANYQAPPEKTIEEIMAADQEDESLRRYKEALLGAAQTEKIIVEPNDPRKVIVKKLALV 77

Human    79 CSSAPGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTD 143
            .... ..:||||||||...|||.||:||||:|:::|.|.|.||||.|:||:|.|.|.||.:||..
  Fly    78 VEGR-DDMELDLTGDLSQLKKQLFVIKEGVQYKVRIDFIVQREIVHGLKYVQKTSRLGVNVDKMK 141

Human   144 YMTTTRP 150
            :|..:.|
  Fly   142 HMVGSYP 148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARHGDIA	NP_001288171.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		6/17 (35%)
		Rho_GDI	19..>145	CDD:280310	65/129 (50%)
RhoGDI	NP_001262080.1	Rho_GDI	14..199	CDD:280310	67/136 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147091
Domainoid	1	1.000	197	1.000	Domainoid score	I3096
eggNOG	1	0.900	-	-		E1_KOG3205
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H908
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3769
Isobase	1	0.950	-	0	Normalized mean entropy	S950
OMA	1	1.010	-	-		QHG54245
OrthoDB	1	1.010	-	-		D1265661at2759
OrthoFinder	1	1.000	-	-		FOG0001289
OrthoInspector	1	1.000	-	-		otm40282
orthoMCL	1	0.900	-	-		OOG6_102354
Panther	1	1.100	-	-	O	PTHR10980
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2126
SonicParanoid	1	1.000	-	-		X792
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750