DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5048 and Dnaaf6

DIOPT Version :9

Sequence 1:	NP_648712.1	Gene:	CG5048 / 39598	FlyBaseID:	FBgn0036437	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_083338.1	Gene:	Dnaaf6 / 74708	MGIID:	1921958	Length:	218	Species:	Mus musculus

Alignment Length:	202	Identity:	62/202 - (30%)
Similarity:	101/202 - (50%)	Gaps:	27/202 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LKMLQGLLNPNQRRGGIDYSSSEDEEESMVVNKMNPGTIGRPNGEDGTAKGKKKKK-PNPLCTPL 73
            |:.|..|||| :...|.|:   |..:.|..:..|.||.||.|       |.|:.|. |.|
Mouse    37 LQALSSLLNP-EEEDGFDF---EQGQCSFTIGAMGPGNIGPP-------KAKESKAIPEP----- 85

  Fly    74 VEEEKKQPESLEEWQDQQEKEDM---DILESRKTPEYTMTYRQAVGTEDVFLQMGNRTGSSASCE 135
                 :..||...|..::..|..   ||.:.|:.|:|.:.::|.||||||:|.:..:..|:|.|:
Mouse    86 -----RSDESENIWNPEEVPEGAEHDDIWDVREIPDYEIVFQQTVGTEDVYLGLTRKDPSTACCQ 145

  Fly   136 DLILEVSLPDEEMTADKMSLSLQETELDLGTCLYRLRLPLPHPVNVDRCHAKYDSELKKLRLTLR 200
            :|::::.||:  ....::.:.:||..|||.|...:|.:..|.||..:...|.|..|.:.|.:.:.
Mouse   146 ELVVKIKLPN--TNPSEIQIDIQEMLLDLRTPRKKLLVNFPQPVERNSARASYIWEAETLEVRMT 208

  Fly   201 LQRELDY 207
            :||:||:
Mouse   209 VQRDLDF 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5048	NP_648712.1	alpha-crystallin-Hsps_p23-like	<104..191	CDD:294116	28/86 (33%)
Dnaaf6	NP_083338.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..103		15/53 (28%)
Dnaaf6	NP_083338.1	alpha-crystallin-Hsps_p23-like	<146..209	CDD:294116	17/64 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837917
Domainoid	1	1.000	62	1.000	Domainoid score	I10285
eggNOG	1	0.900	-	-		E1_2CJGJ
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16553
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5088
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57044
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007485
OrthoInspector	1	1.000	-	-		otm42350
orthoMCL	1	0.900	-	-		OOG6_104720
Panther	1	1.100	-	-	LDO	PTHR21083
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5667
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790