DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5048 and dnaaf6

DIOPT Version :9

Sequence 1:	NP_648712.1	Gene:	CG5048 / 39598	FlyBaseID:	FBgn0036437	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_001002309.1	Gene:	dnaaf6 / 432386	ZFINID:	ZDB-GENE-040722-2	Length:	194	Species:	Danio rerio

Alignment Length:	214	Identity:	68/214 - (31%)
Similarity:	112/214 - (52%)	Gaps:	33/214 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SIFDHPEQLKMLQGLLNPNQRRGGIDYSSSEDEEESMVVN---KMNPGTIGRPNGEDGTAKGKKK 63
            |:.|    |:.|..||:..:        .:::|||.:.:.   :|.||.||.|....|..||.
Zfish     6 SVHD----LQALSALLSKPK--------DNDEEEEDLTLQPMARMGPGHIGPPAAPSGKNKGS-- 56

  Fly    64 KKPNPLCTPLVEEEKKQPESLEEWQDQQEKEDM---DILESRKTPEYTMTYRQAVGTEDVFLQMG 125
                  .:..|::..|     :.|.:.:..|..   |:.:.|..|||.:..:|:|||||:||.:.
Zfish    57 ------TSAYVKKNSK-----DIWDEAEVTEGAHFDDLNDPRPQPEYEIVLKQSVGTEDLFLGLS 110

  Fly   126 NRTGSSASCEDLILEVSLPDEEMTADKMSLSLQETELDLGTCLYRLRLPLPHPVNVDRCHAKYDS 190
            .:..||..||.:::.|.|||.: |:| :.|.::||.|||.|..|:|.|.|||||:....:|::.:
Zfish   111 RKDPSSMCCESMLVRVKLPDTK-TSD-LVLDVRETFLDLRTPKYKLGLHLPHPVHKQEGNARFIT 173

  Fly   191 ELKKLRLTLRLQRELDYVN 209
            |.::|.:||.:.|.:|.:|
Zfish   174 EREELEITLPMNRPMDCIN 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5048	NP_648712.1	alpha-crystallin-Hsps_p23-like	<104..191	CDD:294116	37/86 (43%)
dnaaf6	NP_001002309.1	alpha-crystallin-Hsps_p23-like	<45..183	CDD:294116	50/152 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581706
Domainoid	1	1.000	77	1.000	Domainoid score	I8850
eggNOG	1	0.900	-	-		E1_2CJGJ
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16553
Inparanoid	1	1.050	97	1.000	Inparanoid score	I5035
OMA	1	1.010	-	-		QHG57044
OrthoDB	1	1.010	-	-		D1561656at2759
OrthoFinder	1	1.000	-	-		FOG0007485
OrthoInspector	1	1.000	-	-		oto40868
orthoMCL	1	0.900	-	-		OOG6_104720
Panther	1	1.100	-	-	LDO	PTHR21083
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5667
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800