DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5048 and Dnaaf6b

DIOPT Version :9

Sequence 1:	NP_648712.1	Gene:	CG5048 / 39598	FlyBaseID:	FBgn0036437	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_808589.1	Gene:	Dnaaf6b / 331537	MGIID:	3607720	Length:	218	Species:	Mus musculus

Alignment Length:	202	Identity:	60/202 - (29%)
Similarity:	99/202 - (49%)	Gaps:	27/202 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LKMLQGLLNPNQRRGGIDYSSSEDEEESMVVNKMNPGTIGRPNGEDGTAKGKKKKK-PNPLCTPL 73
            |:.|..||||.:.    |....|..:.:..:..|.||.||.|       |.|:.|. |.|
Mouse    37 LQALASLLNPEEE----DDFDFEQGQCTSTIRAMGPGNIGPP-------KAKESKAIPEP----- 85

  Fly    74 VEEEKKQPESLEEWQDQQEK---EDMDILESRKTPEYTMTYRQAVGTEDVFLQMGNRTGSSASCE 135
                 :..||...|..::..   |..||.:.|:.|:|.:.::|.|||||::|.:..:..|:|.|:
Mouse    86 -----RSDESENIWNPEEVPEGGEHDDIWDVREIPDYEIVFQQTVGTEDIYLGLTGKDPSTACCQ 145

  Fly   136 DLILEVSLPDEEMTADKMSLSLQETELDLGTCLYRLRLPLPHPVNVDRCHAKYDSELKKLRLTLR 200
            :|::::.||:  ....::.:.:||..|||.|...:|.:..|.||..:...|.|..|.:.|.:.:.
Mouse   146 ELVVKIKLPN--TNPSEIQIDIQEMLLDLRTPKKKLLVNFPQPVERNSARASYIWEAETLEVRMT 208

  Fly   201 LQRELDY 207
            |||:||:
Mouse   209 LQRDLDF 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5048	NP_648712.1	alpha-crystallin-Hsps_p23-like	<104..191	CDD:294116	27/86 (31%)
Dnaaf6b	NP_808589.1	alpha-crystallin-Hsps_p23-like	<146..207	CDD:294116	17/62 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837916
Domainoid	1	1.000	62	1.000	Domainoid score	I10285
eggNOG	1	0.900	-	-		E1_2CJGJ
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16553
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5088
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57044
OrthoDB	1	1.010	-	-		D1561656at2759
OrthoFinder	1	1.000	-	-		FOG0007485
OrthoInspector	1	1.000	-	-		otm42350
orthoMCL	1	0.900	-	-		OOG6_104720
Panther	1	1.100	-	-	O	PTHR21083
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5667
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800