DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and f7

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001072819.1	Gene:	f7 / 780280	XenbaseID:	XB-GENE-5787186	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	297	Identity:	111/297 - (37%)
Similarity:	150/297 - (50%)	Gaps:	46/297 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 FNRNNSPAAQNQTSPTCSCR-------------------CGE------RNDESRIVGGTTTGVSE 138
            |..:||     .||..|||.                   ||:      .|..:|||||......|
Frog   163 FCHDNS-----STSRQCSCAEGYKLGADGLSCEPTVNYPCGKIPVLKNVNKRARIVGGDMCPKGE 222

  Fly   139 YPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFGEH----DRCNDKERPETRFV 199
            .||.|.|.|...|.||||||...:|:|||||:|......:.|..|||    ....::|...::.:
Frog   223 CPWQALLMYNEIFICGGTLIAPNWVITAAHCLKPLPENKLTVVLGEHRIGTPEGTEQESKVSKII 287

  Fly   200 LRA--FSQKFSFSNFDNDIALLRLNDRVPITSFIRPICLPRVE-QRQDLFVGTKAIATGWGTLKE 261
            :..  :..|   :|.|||||||:|...|..|.::.|:|||..: ..|:|.....:..:|||.|.|
Frog   288 MHEHYYGSK---TNNDNDIALLKLTTPVNYTDYVVPLCLPEKQFAVQELLSIRYSTVSGWGRLLE 349

  Fly   262 DGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDD 326
            .|....|||.|::|.:...:|:.|   ||..|::||.|:||.. |.:|||:||||||.. .:..:
Frog   350 SGATPELLQRVQLPRVKTQDCIRQ---TQMNISQNMFCAGYTD-GSKDSCKGDSGGPHA-TQYKN 409

  Fly   327 KRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWIVEN 363
            ..| ..||||||.|||:....||||||::|.:||.||
Frog   410 THF-LTGIVSWGLGCAKKEKYGVYTRVSRYTEWIKEN 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	96/239 (40%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	97/241 (40%)
f7	NP_001072819.1	Gla	67..107	CDD:366184
		EGF_CA	108..144	CDD:238011
		FXa_inhibition	153..189	CDD:373209	8/30 (27%)
		Tryp_SPc	212..445	CDD:238113	97/241 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910