DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and tmprss4a

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_005157547.1	Gene:	tmprss4a / 777630	ZFINID:	ZDB-GENE-061103-631	Length:	458	Species:	Danio rerio

Alignment Length:	256	Identity:	93/256 - (36%)
Similarity:	137/256 - (53%)	Gaps:	22/256 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 SPTCSCRCGERNDESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKG---- 172
            |.:||..||...::.|||||....::.:||...|.|..:..|||:|:...:|:|||||..|
Zfish   208 SLSCSADCGLSRNQDRIVGGKDADIANWPWQVSLQYSGQHTCGGSLVTPNWVVTAAHCFNGDGRK 272

  Fly   173 --FMWFMIK-VTFGEHDRCNDKERPETRFVLRAFSQKFSFSNFDNDIALLRLNDRVPITSFIRPI 234
              ..|.::. :|:       ....|.:.......:..:..:..|.||.:::|...:.::...||:
Zfish   273 ALSRWTVVSGITY-------LSSTPSSYVKEIIVNSNYKPAESDFDITMIKLQSPITLSESRRPV 330

  Fly   235 CLPRVEQRQDLFVGTKAIATGWGTLKE-DGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMM 298
            |||  .|...|..|...:.||||.:.| .|..|.:||:.::.|:|:.:|.:.|.|... ||..|:
Zfish   331 CLP--PQNLGLKGGDGLVVTGWGHMAEKGGSLSSMLQKAQIQVIDSAQCSSPTVYGSS-ITPRMI 392

  Fly   299 CSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDW 359
            |:|.. .||.|:||||||||||.|.   .|:..:|:||||.|||||.:|||||.|.:.|||
Zfish   393 CAGVM-AGGVDACQGDSGGPLVHLA---DRWVLVGVVSWGVGCARPGFPGVYTNVDQMLDW 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	88/241 (37%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	87/240 (36%)
tmprss4a	XP_005157547.1	LDLa	74..105	CDD:238060
		SRCR_2	121..218	CDD:295335	5/9 (56%)
		Tryp_SPc	223..449	CDD:214473	86/239 (36%)
		Tryp_SPc	224..449	CDD:238113	85/238 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I4005
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6379
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.960