DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and f9b

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001035400.1	Gene:	f9b / 678552	ZFINID:	ZDB-GENE-060421-7346	Length:	507	Species:	Danio rerio

Alignment Length:	335	Identity:	108/335 - (32%)
Similarity:	171/335 - (51%)	Gaps:	50/335 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TSTATSSLSSIPG-KYQALGAAHHQAKKLKIGDVNASSSDANKPVFRQNPIKNWFGAFNRNNSPA 106
            |.....::|.|.| :|...     ::....:.::|::|:..|             ...|.::||.
Zfish   196 TVNQNQTISHINGTEYNTT-----ESSPTDLSEMNSTSTPRN-------------SLQNVSSSPI 242

  Fly   107 AQNQTSPTCSCRCGERNDESRIVGGTTTGVSEYPW-MARLSYFNRF-YCGGTLINDRYVLTAAHC 169
            ..|..:.|        |::.|||||......|.|| :..|...|:. :|||:|:::.:|:|||||
Zfish   243 LTNINNTT--------NNKYRIVGGDEAIPGEIPWQVVFLEKVNKIVFCGGSLLSEEWVITAAHC 299

  Fly   170 VKGFMW-FMIKVTFGEHDRCNDKERPETRFVLRAF-------SQKFSFSNFDNDIALLRLNDRVP 226
            |:|... |.|:|  |||| .:..|..|:...:..:       ||:   |.:::|||||:|...|.
Zfish   300 VEGKQGSFFIRV--GEHD-VSKMEGTESDHGIEEYHIHPRYNSQR---SLYNHDIALLKLKKPVI 358

  Fly   227 ITSFIRPICLPRVEQRQDLFVGTK-AIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQ 290
            :..:..||||...:..::|....: ::.:|||.|:..|..|.:||:||:|.:|..:|...:.
Zfish   359 LFDYAVPICLGSKDFTENLLQSAENSLVSGWGRLRYGGIESNVLQKVELPYVDRIKCKGSST--- 420

  Fly   291 KMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTK 355
            ..|::.|.|:||..| .:|:||||||||.. .|..|..| ..||||||..||:....|:|||::|
Zfish   421 DSISRFMFCAGYSTV-RKDACQGDSGGPHA-TRYKDTWF-LTGIVSWGEECAKEGKYGIYTRISK 482

  Fly   356 YLDWIVENSR 365
            |:.||...:|
Zfish   483 YMAWITNITR 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	91/243 (37%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	92/245 (38%)
f9b	NP_001035400.1	GLA	23..86	CDD:214503
		EGF_CA	88..124	CDD:238011
		FXa_inhibition	131..167	CDD:291342
		Tryp_SPc	255..487	CDD:214473	91/243 (37%)
		Tryp_SPc	256..490	CDD:238113	92/245 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910