DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4914 and PRSS56

DIOPT Version :9

Sequence 1:NP_648711.1 Gene:CG4914 / 39597 FlyBaseID:FBgn0036436 Length:374 Species:Drosophila melanogaster
Sequence 2:NP_001356777.1 Gene:PRSS56 / 646960 HGNCID:39433 Length:604 Species:Homo sapiens


Alignment Length:345 Identity:114/345 - (33%)
Similarity:153/345 - (44%) Gaps:53/345 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 TSAPPATSTATSSLSSIPGKYQALGAAHHQAK------KLKIGDVNASSSDANKPVFRQNPIKNW 95
            |..||:.....|:..:     |||.||...|:      .::|...:.....:.:|          
Human    24 TRLPPSALQVLSAQGT-----QALQAAQRSAQWAINRVAMEIQHRSHECRGSGRP---------- 73

  Fly    96 FGAFNRNNSPAAQNQTSPTCSCRCGERNDES--------RIVGGTTTGVSEYPWMARLSYFNRFY 152
                    .|.|..|..|... .||||...:        |||||:......:||:.||....:..
Human    74 --------RPQALLQDPPEPG-PCGERRPSTANVTRAHGRIVGGSAAPPGAWPWLVRLQLGGQPL 129

  Fly   153 CGGTLINDRYVLTAAHCVKG----FMWFMIKVTFGEHDRCNDKERPETRFVLRAFSQKFSFSNFD 213
            |||.|:...:|||||||..|    .:|   .||..|..|....|......:|.  ..||....|.
Human   130 CGGVLVAASWVLTAAHCFVGAPNELLW---TVTLAEGSRGEQAEEVPVNRILP--HPKFDPRTFH 189

  Fly   214 NDIALLRLNDRVPITSFIRPICLPRVEQRQDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVLD 278
            ||:||::|...|......||:|||  ::.|:...||.....|||.|.|||..:..::|..||:|.
Human   190 NDLALVQLWTPVSPGGSARPVCLP--QEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLS 252

  Fly   279 NDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQI-GIVSWGNGCA 342
            .|.|  :......:....|:|:||. .||.|||||||||||....|..:..|.: |:.|||:||.
Human   253 TDTC--RRALGPGLRPSTMLCAGYL-AGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCG 314

  Fly   343 RPNYPGVYTRVTKYLDWIVE 362
            .|..|||||||..:.||:.|
Human   315 EPGKPGVYTRVAVFKDWLQE 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4914NP_648711.1 Tryp_SPc 127..360 CDD:214473 92/237 (39%)
Tryp_SPc 128..363 CDD:238113 93/240 (39%)
PRSS56NP_001356777.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 64..96 9/50 (18%)
Tryp_SPc 105..335 CDD:238113 93/240 (39%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 443..475
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 574..604
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 1 1.000 - - H79885
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001240
OrthoInspector 1 1.000 - - otm42230
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X11
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.910

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