Protein Alignment CG4914 and PRSS22

DIOPT Version :10

• Sequence 1: NP_648711.1
• Gene: CG4914 / 39597
• FlyBaseID: FBgn0036436
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 101/358 - (28%)
• Similarity: 153/358 - (42%)
• Gaps: 80/358 - (22%)

  Fly    22 TAATSATPATPATPATSAPPATSTATSSLSSIPGKYQALGAAHHQAKKLKIGDVNASSSDANKPV 86
            :.|..|.|.....||...|     ....|.|:||.::|.|
Human    97 SCAARAWPGPRKCPAGRGP-----GVERLESLPGHWRARG------------------------- 131

  Fly    87 FRQNPIKNWFGAFNRNNSPAAQNQTSPTCSCRCGERNDESRIVGGTTTGVSEYPWMARLSYFNRF 151
                           ::.||..|.........||:....:|:|||..:..||:||:..:......
Human   132 ---------------SSPPAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTH 181

  Fly   152 YCGGTLINDRYVLTAAHCVKGFM--WFMIKVTFGEHDRCNDKERPETRFVLRAFSQKFSFSNFD- 213
            :|.|:|:..|:|:|||||.|..:  .::..|..|.....|...|          |||...:..:
Human   182 HCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSR----------SQKVGVAWVEP 236

  Fly   214 -----------NDIALLRLNDRVPITSFIRPICLPRVEQRQDLFVGTKAIATGWGTLKEDGKP-- 265
                       .||||:||...:..:..:.|||||  :....|...|....:|||:: :||.|
Human   237 HPVYSWKEGACADIALVRLERSIQFSERVLPICLP--DASIHLPPNTHCWISGWGSI-QDGVPLP 298

  Fly   266 -SCLLQEVEVPVLDNDEC--VAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDK 327
             ...||:::||::|::.|  :......|..||::|:|:||. .|.||:|.|||||||  :...|.
Human   299 HPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYL-EGERDACLGDSGGPL--MCQVDG 360

  Fly   328 RFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWI 360
            .:...||:|||.|||..|.||||..::.:..|:
Human   361 AWLLAGIISWGEGCAERNRPGVYISLSAHRSWV 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	83/252 (33%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	83/252 (33%)