DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4914 and zgc:100868

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_005164187.1	Gene:	zgc:100868 / 554458	ZFINID:	ZDB-GENE-040801-33	Length:	654	Species:	Danio rerio

Alignment Length:	291	Identity:	106/291 - (36%)
Similarity:	137/291 - (47%)	Gaps:	74/291 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 CGERNDESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFG 183
            ||.....||||||....|..:||...|......:|||:|||::::||||||.
Zfish    28 CGTAPLNSRIVGGQNAPVGAWPWQVSLQRDGSHFCGGSLINNQWILTAAHCF------------- 79

  Fly   184 EHDRCNDKERPETRFVL-----------RAFSQKFSFSNF-----------DNDIALLRLNDRVP 226
                    ..|.|..:|           .::|...:.||.           ||||.||:|...|.
Zfish    80 --------PNPSTTGLLVYLGLQKLASFESYSMSSAVSNIIKHPNYNSDTEDNDITLLQLASTVS 136

  Fly   227 ITSFIRPICLPRVEQRQDLFVGTKAIATGWG------TLKEDGKPSCLLQEVEVPVLDNDECVAQ 285
            .:::||||||...:  ...|.||....||||      :|...|    .||||:||::.|.:|  .
Zfish   137 FSNYIRPICLAASD--STFFNGTLVWITGWGNTATGVSLPSPG----TLQEVQVPIVGNRKC--N 193

  Fly   286 TNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVY 350
            ..|....||.||:|:|.. .||:||||||||||:|  ......:.|.||||:|.|||:||:||||
Zfish   194 CLYGVSKITDNMVCAGLL-QGGKDSCQGDSGGPMV--SKQGSVWIQSGIVSFGTGCAQPNFPGVY 255

  Fly   351 TRVTKYLDWIVE--------------NSRDG 367
            |||:||..||.:              |..||
Zfish   256 TRVSKYQSWIQQRITTTQPGFVMYNSNGTDG 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	98/260 (38%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	99/276 (36%)
zgc:100868	XP_005164187.1	Tryp_SPc	36..265	CDD:214473	98/260 (38%)
		Tryp_SPc	37..267	CDD:238113	99/261 (38%)
		Tryp_SPc	331..509	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910