DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and prss27

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	255	Identity:	90/255 - (35%)
Similarity:	134/255 - (52%)	Gaps:	15/255 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 SCRCGERNDESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCV-KGFMWFMIK 179
            |..||:.....|||||......|:||...:.|.|...|||:|::..:|::||||. :.:....::
Frog   408 STGCGQPAFSDRIVGGNNAVFGEWPWQVSIVYQNSHICGGSLVSSNWVVSAAHCFPRSYKIENMQ 472

  Fly   180 VTFGEHDRCNDKERPETRFVLRAFSQK-FSFSNFDNDIALLRLNDRVPITSFIRPICLPRVEQRQ 243
            |..|.....|.........|.|..:.. ::......|||::.:...|..:|:|.|||:|..  .:
Frog   473 VLLGCFALMNLTSDAVIIRVKRVITYPLYTGEGSSGDIAMVEMESPVTYSSYILPICIPLT--NE 535

  Fly   244 DLFVGTKAIATGWGTLKEDG--KPSCLLQEVEVPVLDNDECVAQTNYTQ------KMITKNMMCS 300
            |...|.....||||.::.|.  .|...|||||||:::...|....:|..      :::..:|:|:
Frog   536 DFPSGKMCWVTGWGNIQSDVSLSPPYPLQEVEVPLVNASSCDTMYHYNSDLNPATQLVHDDMICA 600

  Fly   301 GYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWI 360
            ||| .|.:|:|||||||||. .:..:..| ..||||||:|||:||.|||||:|:.:..||
Frog   601 GYP-EGQKDACQGDSGGPLA-CKSGNYWF-LTGIVSWGDGCAQPNRPGVYTKVSSFSSWI 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	85/242 (35%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	86/243 (35%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	86/243 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3837
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.970