DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and ea

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	296	Identity:	103/296 - (34%)
Similarity:	139/296 - (46%)	Gaps:	52/296 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 PAAQNQTSPTCSCRCGERND--ESRIVGGTTTGVSEYPWMARLSYFNR-----FYCGGTLINDRY 162
            |...|.||.:.....|:..:  .:||.||..|.:.|:||||.:.|...     .:|||:||:.||
  Fly   103 PPKPNVTSNSLLPLPGQCGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRY 167

  Fly   163 VLTAAHCVKGFM----WFMIKVTFGEHDR-----CN------------------DKERPETRFVL 200
            |:||:|||.|..    |.:..|..||.|.     |.                  ::..|...::.
  Fly   168 VITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIP 232

  Fly   201 RAFSQKFSFSNFDNDIALLRLNDRVPITSFIRPICLP-RVEQRQDLFVGTKAIATGWGTLKEDGK 264
            .:.:|.       ||||||||..:|..|.|:|||||| .|..|...|.|......|||. .|...
  Fly   233 ASKNQV-------NDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGK-TEQLS 289

  Fly   265 PSCLLQEVEVPVLDNDECVAQTNYTQK--MITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPD-- 325
            .|.|..:..|.....|||  |..|:.:  ::....||:|  |..|.|||:|||||||:.|..:
  Fly   290 ASNLKLKAAVEGFRMDEC--QNVYSSQDILLEDTQMCAG--GKEGVDSCRGDSGGPLIGLDTNKV 350

  Fly   326 DKRFEQIGIVSWG-NGCARPNYPGVYTRVTKYLDWI 360
            :..:...|:||:| ..|....:|||||.|.||:|||
  Fly   351 NTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWI 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	96/270 (36%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	97/271 (36%)
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	96/270 (36%)
		Tryp_SPc	128..389	CDD:238113	97/271 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	3	3.010